Predictors of Outcome in Patients With Pleural Infection at Sohag University Hospital

NCT06141174 | Unknown

• 1 other identifier: Soh-med-23-10-08ms
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

pleural infection remains a common medical problem with significant mortality and morbidity despite a better undrstanding of the aetiology , pathophysiology and recent advances in management approaches . the cornerstones of the managment op pleural infection include early identification of cases and accurate diagnosis . suitable antibiotic therapy , nutrition managment , efficient drainage of infected collection via chest tube with or without adjunctive therapies including intrapleural agents and ultimately surgical managment .

Conditions

Pleural Infection

Outcome Measures

Primary Outcomes (1)

• lenght of hospital stay

  lenght of hospital stay since admission up to improvement

  1 month

Secondary Outcomes (1)

• mortality rate

  up to 30 days , 3 months

Interventions

disease outcome ( mortality and length of stay ) OTHER

insertion of intercostal tube to drain pleural collection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients more than 18 years old with pleural infection

You may qualify if:

• patients more than 18 years old with pleural infection

You may not qualify if:

• hemothorax
• chest trauma within 3 month
• underwent thoracic surgery within 60 days

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university Hospital

Sohag, Sohag, Egypt

RECRUITING

Related Publications (4)

• Gould J. Pleural infection: a case where clinical improvement was misleading. BMJ Case Rep. 2013 Apr 18;2013:bcr2013008700. doi: 10.1136/bcr-2013-008700.

  PMID: 23605824 BACKGROUND

• Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ. Intrapleural use of tissue plasminogen activator and DNase in pleural infection. N Engl J Med. 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740.

  PMID: 21830966 BACKGROUND

• Davies CW, Gleeson FV, Davies RJ; Pleural Diseases Group, Standards of Care Committee, British Thoracic Society. BTS guidelines for the management of pleural infection. Thorax. 2003 May;58 Suppl 2(Suppl 2):ii18-28. doi: 10.1136/thorax.58.suppl_2.ii18. No abstract available.

  PMID: 12728147 BACKGROUND

• Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group. Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. No abstract available.

  PMID: 20696693 BACKGROUND

MeSH Terms

Interventions

Mortality; Length of Stay

Intervention Hierarchy (Ancestors)

Vital Statistics; Data Collection; Epidemiologic Methods; Investigative Techniques; Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health; Hospitalization; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Central Study Contacts

amany e hashem, resident

CONTACT

01145694321; amanyhashem@med.sohag.edu.eg

mona t hussein, professor

CONTACT

01028068879

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at chest diseases and tuberculosis

Study Record Dates

• First Submitted: November 15, 2023
• First Posted: November 21, 2023
• Study Start: November 1, 2023
• Primary Completion: May 1, 2024
• Study Completion: May 1, 2024
• Last Updated: November 21, 2023

Record last verified: 2023-11

Locations

EG (1)