SonoElastography of Median Nerve in Rheumatoid Arthritis

NCT06135129 | Unknown

• 1 other identifier: Elastography median nerve
• Study Type: observational
• Target: 71
• Locations: 0 countries
• Sites: N/A

Brief Summary

To assess the role of ultrasonography and SE in detecting the median nerve changes before progression to CTS in patients with RA.

Conditions

Rheumatoid Arthritis

Keywords

Elastography

Outcome Measures

Primary Outcomes (1)

• To assess the role of ultrasonography and SE in detecting the median nerve changes before progression to CTS in patients with RA.

  The accuracy of Sonoelastography to detect median nerve changes in rheumatoid arthritis patients

  Baseline

Interventions

Sonoelastography DEVICE

Sonoelastography (SE) is a new ultrasound-based method measure the stiffness or elasticity of tissues, has no hazards on poatients.

Eligibility Criteria

• Age: 1 Year - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients diagnosed with RA and ruling out CTS by clinical evaluation

You may qualify if:

• All patients diagnosed with RA and ruling out CTS by clinical evaluation that included Phalen's test, a manual muscle test of the abductor's muscle, and a search for Tinel-like signs and thenar muscle atrophy. Controls - Age- and sex- matched cases without RA undergoing US for causes unrelated to RA or CTS. The criteria for RA were adopted from The American Rheumatism Association (1987) for the classification of RA.

You may not qualify if:

• History of a condition other than RA that could cause CTS (e.g., diabetes mellitus, acute trauma, pregnancy ,hypothyroidism, hyperthyroidism, connective tissue disease)History of surgery for a wrist or hand fracture.
• History of other systemic neurological disorders or radiculopathy Bifid median nerve or any mass lesion identified on US examination Pregnant patients were excluded.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Hammer HB, Haavardsholm EA, Kvien TK. Ultrasonographic measurement of the median nerve in patients with rheumatoid arthritis without symptoms or signs of carpal tunnel syndrome. Ann Rheum Dis. 2007 Jun;66(6):825-7. doi: 10.1136/ard.2006.055988. Epub 2006 Dec 14.

  PMID: 17170055 BACKGROUND

• Atan Uzun C, Sunar I, Gunendi Z, Gogus FN. Comparison of the median and ulnar nerves of rheumatoid arthritis patients and healthy subjects by ultrasound. Arch Rheumatol. 2022 Oct 21;38(2):183-188. doi: 10.46497/ArchRheumatol.2023.9027. eCollection 2023 Jun.

  PMID: 37680523 RESULT

MeSH Terms

Conditions

Arthritis, Rheumatoid

Interventions

Elasticity Imaging Techniques

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Ultrasonography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Central Study Contacts

Marco Magdy, Resident doctor

CONTACT

01270777143; marcomagdy1997@gmail.com

Ahmed Mustafa, professor

CONTACT

01000024182; ahmed.hamed2@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor

Study Record Dates

• First Submitted: November 12, 2023
• First Posted: November 18, 2023
• Study Start: December 1, 2023
• Primary Completion: December 1, 2024
• Study Completion: January 1, 2025
• Last Updated: November 18, 2023

Record last verified: 2023-11