Observation and Interactions Between Cardio-respiratory and Motor Transitions at the Limits of Moderate Exercise.

NCT06132724 | Completed

• 1 other identifier: 38RC23.0263
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about physiological transitions around the limit of moderate exercise intensity on cardiac, respiratory and motor modalities, in healthy population. The main questions it aims to answer is:

• is it possible to define criteria on cardiac, respiratory and motor modalities to identify transitions?
• are those transitions visible on embedded and non-intrusive monitoring equipment?
• are those identified transitions somehow connected to first ventilatory threshold (VT1)? Participants will do a sub-maximal effort test on cycloergometer calibrated to make them cross their first ventilatory threshold.

Conditions

Healthy

Keywords

Retraining; Physical Activity; First Ventilatory Threshold; Moderate Intensity Domain; Physiological Transitions; Motricity; Cardiorespiratory; Connected Objects

Outcome Measures

Primary Outcomes (1)

• Database of physiological signals

  Synchronized signals from embedded and non-intrusive connected devices for cardiorespiratory and motricity measurements and equivalent laboratory measurements during cycling on a cyclo-ergometer

  20 minutes

Secondary Outcomes (5)

• Evaluation of the feeling of wearing equipment

  15 minutes

• Criteria for the observation of a respiratory transition

  6 months

• Criteria for the observation of a cardiac transition

  6 months

• Criteria for the observation of a motricity transition

  6 months

• Multi-modal prediction of the first ventilatory threshold

  6 months

Study Arms (1)

Healthy Volunteers

Subjects who will agree to participate to the study will be healthy subject with no particular antecedents. Subjects will be enroled for two sessions with a 20 min monitoring phase in each session, to coect physiological data with non invasive sensors.

Other: Signal acquisition

Interventions

Signal acquisition OTHER

Synchronized signals from cardiac, respiratory and movements non invasive measurements. One acquisition is 20 minutes long, and each subject participate to two sessions, separated by 1 to 15 days.

Healthy Volunteers

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Heathy volunteers with various physical conditions

You may qualify if:

• Capability to cycle during 20min
• No contraindication to cycling at a moderate pace
• No acute pathology (less than 2 years old)
• No cardiac or respiratory chronic pathology
• No locomotive problem on the spine or the lower limbs
• No recent injuries (less than 2 months)
• Stature compatible with the use of the plethysmography t-shirt

You may not qualify if:

• Pregnant (urine strip test) or breastfeeding women
• Persons referred to in articles L1121-5 to L1121-8 of the CSP (protected persons) person deprived of liberty by judicial or administrative decision, person subject to a legal protection measure
• Subject being excluded from another study
• Subject who reached the ceiling of 4500 euros due to their participation in other studies involving human in the past 12 months

Sponsors & Collaborators

• University Hospital, Grenoble: lead
• TIMC-IMAG: collaborator
• University Grenoble Alps: collaborator

Study Sites (1)

Plateforme PRETA P3I

Grenoble, 38043, France

Location

Related Publications (6)

• Blair SN. Physical inactivity: the biggest public health problem of the 21st century. Br J Sports Med. 2009 Jan;43(1):1-2. No abstract available.

  PMID: 19136507 BACKGROUND

• Pisot R. Physical Inactivity - the Human Health's Greatest Enemy. Zdr Varst. 2021 Dec 27;61(1):1-5. doi: 10.2478/sjph-2022-0002. eCollection 2022 Mar.

  PMID: 35111260 BACKGROUND

• Meyler S, Bottoms L, Muniz-Pumares D. Biological and methodological factors affecting V̇O2max response variability to endurance training and the influence of exercise intensity prescription. Exp Physiol. 2021 Jul;106(7):1410-1424. doi: 10.1113/EP089565. Epub 2021 Jun 8.

  PMID: 34036650 BACKGROUND

• Succi PJ, Dinyer TK, Byrd MT, Bergstrom HC. Comparisons of the Metabolic Intensities at Heart Rate, Gas Exchange, and Ventilatory Thresholds. Int J Exerc Sci. 2020 May 1;13(2):455-469. doi: 10.70252/IBRC8606. eCollection 2020.

  PMID: 32509109 BACKGROUND

• Pouliquen C, Nicolas G, Bideau B, Garo G, Megret A, Delamarche P, Bideau N. Spatiotemporal analysis of 3D kinematic asymmetry in professional cycling during an incremental test to exhaustion. J Sports Sci. 2018 Oct;36(19):2155-2163. doi: 10.1080/02640414.2018.1432066. Epub 2018 Jan 30.

  PMID: 29381424 BACKGROUND

• Jamnick NA, Pettitt RW, Granata C, Pyne DB, Bishop DJ. An Examination and Critique of Current Methods to Determine Exercise Intensity. Sports Med. 2020 Oct;50(10):1729-1756. doi: 10.1007/s40279-020-01322-8.

  PMID: 32729096 BACKGROUND

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 9, 2023
• First Posted: November 15, 2023
• Study Start: December 5, 2023
• Primary Completion: June 11, 2024
• Study Completion: June 11, 2024
• Last Updated: April 1, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)