Vestibulo-Ocular Reflex Function in Individuals With Chronic Motion Sensitivity Cross-Sectional Study

NCT06128707 | Completed DMC

• 1 other identifier: IRB# 5230167
• Study Type: observational
• Target: 59
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic motion sensitivity refers to a sensation of unwellness caused by physical or discerned motion and has a prevalence of 28% in the general population and it is more common in women (27.3%) compared to men. The investigators theorize that individuals with chronic motion sensitivity will have an impaired inner ear reflex and will be less physically active. Hence, the purpose of this study is to;

1. 1.Determine whether the function of an inner ear reflex is different between young adults with/without chronic motion sensitivity
2. 2.Assess relationships between reflex function and balance in young adults with/without CMS
3. 3.Assess relationships between physical activity and balance in young adults with/without CMS.

Conditions

Motion Sickness

Keywords

Chronic motion sensitivity

Outcome Measures

Primary Outcomes (2)

• Bertec vision advantage

  Scores on 4 parametters- Baseline visual acuity (Logarithm of the minimum angle of resolution LogMAR)- A measure of optotype size with lower values signifying smaller optotype size and better vision with the head static, Visual processing time (Mili seconds) this is the time taken to identify the size of the optotype, Dynamic visual acuity (Logarithm of the minimum angle of resolution LogMAR)-A measure of optotype size with lower values signifying smaller optotype size and better vision with the head dynamic, Gaze stability test (Degrees per second), this is the highest speed at which the participant can identify the optotype while the head is moving.

  1 day

• Computerized dynamic posturography with immersion virtual reality

  Average scores under 2 conditions- Condition one- Eye open, Stable platform, Condition 2 Eye open, sway referenced platform. Each condition measured gives a score known as the equillibrum score measured as age matched normative data with higher scores signifying stronger balance , and a lower scores signifying weaker balance

  1 day

Secondary Outcomes (1)

• International Physical activity questionaire short form

  1 day

Other Outcomes (1)

• Motion sickness susceptibility questionnaire short form

  1 day

Study Arms (2)

Chronic Motion sensitivity group

Participants with a self-reported history of chronic motion sensitivity and who scored greater than or equal to the 30th percentile on the Motion sickness susceptibility questionnaire short form.

Non-Chronic Motion sensitivity Group

Participants without a self-reported history of chronic motion sensitivity and who scored less than or equal to the 25th percentile on the Motion sickness susceptibility questionnaire short form.

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be recruited from Loma Linda University and surrounding communities. The study will be conducted in the Loma Linda University Physical Therapy Department's Neuroscience Research Laboratory. Participants between the age of 20 and 30 with and without a self-reported history of chronic motion sensitivity (i.e, experiencing nauseousness and/or dizziness during while using various means of transportation such as, car, train, bus, boat, and airplane and/or, recreational fun-fair rides and/or when exposed to conflicting visual images)

You may qualify if:

• Age 20-40
• With and without a history of CMS

You may not qualify if:

• CNS disorder
• Impaired cervical spine ROM
• Migraines
• Seizures
• Vestibular dysfunction
• Musculoskeletal dysfunction
• Medications causing dizziness

Sponsors & Collaborators

• Loma Linda University: lead

Study Sites (1)

Loma Linda University

Loma Linda, California, 92350, United States

Location

MeSH Terms

Conditions

Motion Sickness

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 25, 2023
• First Posted: November 13, 2023
• Study Start: September 30, 2023
• Primary Completion: February 1, 2024
• Study Completion: February 1, 2024
• Last Updated: October 26, 2024

Record last verified: 2024-10

Locations

US (1)