Psychiatric Disorder in Dysnergic Defecation

NCT06128031 | Completed DMC

• 1 other identifier: psycosis&dyssynergic defecatio
• Study Type: observational
• Target: 148
• Locations: 1 country
• Sites: 1

Brief Summary

Case control observational study conducted on DD patient and healthy control group.

1. 1.evaluate psychiatric disorders among patients with dyssynergic defecation
2. 2.evaluate the effect of delayed diagnosis of dysnergic defecation on the quality of the life

Conditions

Psychiatric Disorder; Dysnergic Defecation

Outcome Measures

Primary Outcomes (1)

• 1-Assess psychiatric disorders among patients with dyssynergic defecation

  Review the different types of psychiatric disorders in patients have diagnosed DD using SCID-5 ,anxiety and depression Hamilton score (from 0-4,zero refer to no symptoms ,4 refer to sever symptoms ), the summation of them show the type and severity of the condition

  through study completion, an average of 1 year

Secondary Outcomes (1)

• The impact of dyssynergia defecation on the quality of the life

  Through study completion, an average of 1 year

Study Arms (1)

Dysnergic defecation disease group

Healthy control population

Other: No intervention

Interventions

No intervention OTHER

No intervention,only observation case control study

Dysnergic defecation disease group

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Disease group suffer from chronic conistipation and diagnosed dyssynergic defecation

You may qualify if:

• patients diagnosed as dyssynergia with anorectal manometric study

You may not qualify if:

• patient with diabetes mellitus ,hypertension ,chronic kidney disease ,and chronic liver disease patients
• patient with neurological disease
• patient with thyroid disease
• patient with past history of psychiatric disorders
• patients with past or current medications or substance induced psychiatric disorders

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Git center

Asyut, Egypt

Location

Related Publications (7)

• Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006 Apr;130(5):1480-91. doi: 10.1053/j.gastro.2005.11.061.

  PMID: 16678561 BACKGROUND

• Rao SS, Mudipalli RS, Stessman M, Zimmerman B. Investigation of the utility of colorectal function tests and Rome II criteria in dyssynergic defecation (Anismus). Neurogastroenterol Motil. 2004 Oct;16(5):589-96. doi: 10.1111/j.1365-2982.2004.00526.x.

  PMID: 15500515 BACKGROUND

• Rao SS, Tuteja AK, Vellema T, Kempf J, Stessman M. Dyssynergic defecation: demographics, symptoms, stool patterns, and quality of life. J Clin Gastroenterol. 2004 Sep;38(8):680-5. doi: 10.1097/01.mcg.0000135929.78074.8c.

  PMID: 15319652 BACKGROUND

• Rao SS, Seaton K, Miller MJ, Schulze K, Brown CK, Paulson J, Zimmerman B. Psychological profiles and quality of life differ between patients with dyssynergia and those with slow transit constipation. J Psychosom Res. 2007 Oct;63(4):441-9. doi: 10.1016/j.jpsychores.2007.05.016. Epub 2007 Aug 1.

  PMID: 17905054 BACKGROUND

• Shear MK, Vander Bilt J, Rucci P, Endicott J, Lydiard B, Otto MW, Pollack MH, Chandler L, Williams J, Ali A, Frank DM. Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress Anxiety. 2001;13(4):166-78.

  PMID: 11413563 BACKGROUND

• Williams JB. A structured interview guide for the Hamilton Depression Rating Scale. Arch Gen Psychiatry. 1988 Aug;45(8):742-7. doi: 10.1001/archpsyc.1988.01800320058007.

  PMID: 3395203 BACKGROUND

• Hosseinzadeh ST, Poorsaadati S, Radkani B, Forootan M. Psychological disorders in patients with chronic constipation. Gastroenterol Hepatol Bed Bench. 2011 Summer;4(3):159-63.

  PMID: 24834176 BACKGROUND

MeSH Terms

Conditions

Mental Disorders

Study Officials

• Bahaa osman, teacher

  Assiut University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 21, 2023
• First Posted: November 13, 2023
• Study Start: November 1, 2023
• Primary Completion: September 1, 2025
• Study Completion: January 31, 2026
• Last Updated: July 1, 2026

Record last verified: 2026-06

Locations

EG (1)