Impact of Eating Beans on Metabolism

NCT06123208 | Completed

• 1 other identifier: GFHNRC513
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.

Conditions

Overweight

Outcome Measures

Primary Outcomes (1)

• Acute effects of consuming processed pulse-based food products on substrate utilization

  The effect of consuming whole beans or bean-derived flour on the use of fat, carbohydrate, and protein for energy will be determine using whole room calorimetry. Fat, carbohydrate, and protein oxidation will be calculated as an absolute amount of grams per day and as a percentage of energy expenditure.

  5 hours after meal consumption

Study Arms (3)

Whole cooked pinto bean meal

EXPERIMENTAL

Participants will consume a meal comprised of 100 grams of whole cooked pinto beans

Other: Whole cooked pinto bean

Pinto bean flour meal

EXPERIMENTAL

Participants will consume a meal comprised of pinto bean flour equivalent to 100 grams of whole cooked pinto beans

Other: Pinto bean flour

Control meal

ACTIVE COMPARATOR

Participants will consume a control meal

Other: Control

Interventions

Whole cooked pinto bean OTHER

Meal comprised of whole cooked pinto beans

Whole cooked pinto bean meal

Pinto bean flour OTHER

Meal comprised of pinto bean flour

Pinto bean flour meal

Control OTHER

Control meal

Control meal

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• BMI \>18.5 or \<30 kg/m2
• Ability to understand and sign the consent form
• Ability of transportation (i.e., participants must be able to provide their own transportation to the Grand Forks Human Nutrition Research Center)
• Non-smoking or use of other tobacco products, including e-cigarettes
• Not taking steroid-based medications; not planning to or currently attempting to gain or lose weight
• All females of childbearing age must be on birth control for a minimum of 3 months prior to start of study

You may not qualify if:

• Inability or unwillingness to consume any food item in the test meals
• More than a 10% change in body weight within the past 2 months
• Participation in a weight loss diet/exercise program
• Current or planned pregnancy
• Lactation
• Uncontrolled hypertension (systolic \>160 mmHg or diastolic \>100 mmHg)
• Diagnosed cardiovascular, pulmonary, skeletal and metabolic diseases
• Fasting glucose \> 100 mg/dL or non-fasting (1-2 hours after eating) \>140 mg/dL
• Using medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)
• Non-English speaking

Sponsors & Collaborators

• USDA Grand Forks Human Nutrition Research Center: lead

Study Sites (1)

USDA Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58203, United States

Location

Related Links

• Grand Forks Human Nutrition Research Center Current Nutrition Studies

MeSH Terms

Conditions

Overweight

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Shanon Casperson, PhD

  USDA Grand Forks Human Nutrition Research Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: FED
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 30, 2023
• First Posted: November 8, 2023
• Study Start: October 30, 2023
• Primary Completion: August 15, 2025
• Study Completion: August 15, 2025
• Last Updated: December 3, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)