Shanghai Ovarian Cancer and Family Care Project
1 other identifier
observational
3,546
1 country
1
Brief Summary
Ovarian cancer is the most lethal gynaecological malignancy, but its incidence in the general population is low. Due to the lack of effective prevention and successful screening approaches, most cases are diagnosed at advanced stages, leading to poor prognosis. In order to address the research requirements pertaining to ovarian cancer, the Shanghai Ovarian Cancer and Family Care Project was established. This initiative offers hospital-based resources for investigating ovarian cancer and high-risk populations. The project comprises an on-going ovarian cancer cohort, a high-risk population cohort, and a healthy population cohort. By leveraging these comprehensive cohorts, the project provides a unique platform for in-depth studies on the detection, prevention, early diagnosis, treatment, and prognosis of ovarian cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2013
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2013
CompletedFirst Submitted
Initial submission to the registry
October 31, 2023
CompletedFirst Posted
Study publicly available on registry
November 7, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 13, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
October 13, 2028
November 7, 2023
October 1, 2023
15.8 years
October 31, 2023
October 31, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Death due to ovarian cancer
Death due to ovarian cancer determined by independent outcomes committee.
From diagnosis of ovarian cancer until October 31, 2028.
Study Arms (3)
Ambispective patient cohort
Patients attending the oncology department require differential diagnosis of ovarian cancer.
High-risk population cohort
Family members of ovarian cancer patients; family history of BRCA mutation-related disease; abnormal findings on ovarian cancer screening; history of ovarian disease and other risk factors.
Healthy control cohort
Healthy women with normal health examination results.
Eligibility Criteria
Patients attending the oncology department; patients with known risk factors for ovarian cancer; healthy individuals who are in good health determined by physical examination.
You may not qualify if:
- Individuals with evidence of another active cancer.
- Individuals who have prior bilateral oophorectomy.
- Individuals who are unwilling or unable to sign the informed consent form.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Shanghai first maternity and infant hospital
Shanghai, Shanghai Municipality, 200120, China
Related Publications (1)
Shi W, Zhang Y, Cheng S, Zhao Y, Li N, Li Y, Yang Y, Ding H, Li Z, Wang Y. Protocol of the SOCFC project: a longitudinal cohort study of ovarian cancer patients, high-risk populations, and healthy controls to identify factors and biomarkers associated with disease diagnosis and prognosis. BMC Cancer. 2025 Feb 26;25(1):355. doi: 10.1186/s12885-025-13652-9.
PMID: 40012035DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 31, 2023
First Posted
November 7, 2023
Study Start
January 1, 2013
Primary Completion (Estimated)
October 13, 2028
Study Completion (Estimated)
October 13, 2028
Last Updated
November 7, 2023
Record last verified: 2023-10