Polypropylene vs Polyglactin in Suturing of the Lung

NCT06115447 | Not Yet Recruiting

• 1 other identifier: polyglactin lung suturing
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Comparative study comparing polypropylene and Polyglactin in suturing of the lung

Conditions

Lung Injury; Bleb Lung; Lung Cancer

Outcome Measures

Primary Outcomes (1)

• duration in days of intercostal tube air leak with each group

  Polypropylene vs Polyglactin

  2 weeks

Study Arms (2)

Polyglactin group

lung suturing with polyglactin

Procedure: lung suturing with polyglactin

Polypropylene Arm

lung suturing with Polypropylene

Procedure: ung suturing with polypropylene

Interventions

lung suturing with polyglactin PROCEDURE

lung suturing with polyglactin

Polyglactin group

ung suturing with polypropylene PROCEDURE

ung suturing with polypropylene

Polypropylene Arm

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients presented to cardiothoracic surgery department and trauma department with the inclusion criteria applied

You may qualify if:

• Patients admitted to Assiut University Hospital And will undergo surgery for lung tear repair.
• Patients admitted to Assiut University Hospital And will undergo surgery for bullectomy or lobectomy.

You may not qualify if:

• Patients with lung injury repaired with a stapler

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Regan T, Lawrence N. Comparison of poliglecaprone-25 and polyglactin-910 in cutaneous surgery. Dermatol Surg. 2013 Sep;39(9):1340-4. doi: 10.1111/dsu.12265. Epub 2013 Aug 13.

  PMID: 23941601 BACKGROUND

• Rendeki S, Molnar TF. Pulmonary contusion. J Thorac Dis. 2019 Feb;11(Suppl 2):S141-S151. doi: 10.21037/jtd.2018.11.53.

  PMID: 30906578 BACKGROUND

• Romby P, Carbon P, Westhof E, Ehresmann C, Ebel JP, Ehresmann B, Giege R. Importance of conserved residues for the conformation of the T-loop in tRNAs. J Biomol Struct Dyn. 1987 Dec;5(3):669-87. doi: 10.1080/07391102.1987.10506419.

  PMID: 3078237 BACKGROUND

MeSH Terms

Conditions

Lung Injury; Blister; Lung Neoplasms

Interventions

Polyglactin 910; Polypropylenes

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Thoracic Injuries; Wounds and Injuries; Skin Diseases, Vesiculobullous; Skin Diseases; Skin and Connective Tissue Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms

Intervention Hierarchy (Ancestors)

Polyesters; Polymers; Macromolecular Substances; Biomedical and Dental Materials; Manufactured Materials; Technology, Industry, and Agriculture; Polyenes; Alkenes; Hydrocarbons, Acyclic; Hydrocarbons; Organic Chemicals; Plastics

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle investigator

Study Record Dates

• First Submitted: October 11, 2023
• First Posted: November 3, 2023
• Study Start: April 15, 2024
• Primary Completion: April 30, 2026
• Study Completion (Estimated): October 30, 2028
• Last Updated: November 3, 2023

Record last verified: 2023-10