NCT02699229

Brief Summary

For this study the investigators are looking to do the following:

  1. 1.To characterize human lung lesions by nonlinear microscopy using ex vivo tissues.
  2. 2.To establish the first spectral/structural database for nonlinear optical microimaging of normal and abnormal lung tissue.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jan 2024

Shorter than P25 for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 2, 2015

Completed
3 months until next milestone

First Posted

Study publicly available on registry

March 4, 2016

Completed
7.9 years until next milestone

Study Start

First participant enrolled

January 11, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 3, 2024

Completed
Last Updated

December 4, 2024

Status Verified

December 1, 2024

Enrollment Period

11 months

First QC Date

December 2, 2015

Last Update Submit

December 3, 2024

Conditions

Lung Cancer

Outcome Measures

Primary Outcomes (1)

  • Nonlinear optical microscopy for cancerous tissue detection in human lung lesions

    Two years

Secondary Outcomes (1)

  • The first spectral/structural database for nonlinear optical micro-imaging of normal and abnormal lung tissue

    Two Years

Study Arms (3)

Malignant

Tissue sample

Benign

Tissue sample

Normal

Tissue Sample

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Lung Cancer Patients

You may qualify if:

  • Age 18 years or older.
  • Patients with confirmed or suspected lung cancer who require lobectomy as part of standard-of-care.

You may not qualify if:

  • Patients deemed on clinical grounds not to be medically fit for a lobectomy
  • Patients where there is a high clinical suspicion of lymphoma (to avoid mixing the data sets).
  • Patients unable to give informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Kazuhiro Yasufuku, MD, PhD

    University Health Network, Toronto

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 2, 2015

First Posted

March 4, 2016

Study Start

January 11, 2024

Primary Completion

December 1, 2024

Study Completion

December 3, 2024

Last Updated

December 4, 2024

Record last verified: 2024-12