Risk Factors and Diagnostic Performance of Predictors as a Screening Technique for Gestational Diabetes Mellitus

NCT06109597 | Completed DMC

• 1 other identifier: fatimahkhobrani
• Study Type: observational
• Target: 247
• Locations: 1 country
• Sites: 1

Brief Summary

Background Gestational diabetes mellitus (GDM) is a condition that can have negative impacts on both mother and baby. Detecting GDM early is crucial, and fasting plasma glucose (FPG) has been suggested as a possible screening method. This retrospective cross-sectional study aims to investigate potential risk factors and complications associated with GDM. Additionally, it aims to establish the diagnostic performance of predictive factors as a screening method for GDM. Methods Data were collected from the medical records of 247 pregnant women who visited high-risk pregnancy outpatient clinics at King Abdul-Aziz Medical City in Jeddah between 2021 and 2022. The study investigated potential risk factors and complications associated with gestational diabetes mellitus (GDM), including impaired fasting glucose/impaired glucose tolerance (IFG/IGT), family history of diabetes mellitus (DM), and medical conditions. Moreover, the study evaluated the diagnostic performance of potential predictors as screening techniques for gestational diabetes mellitus (GDM).

Conditions

Gestational Diabetes

Outcome Measures

Primary Outcomes (1)

• Complications associated with gestational diabetes mellitus

  The study investigated potential risk factors and complications associated with gestational diabetes mellitus (GDM), including impaired fasting glucose/impaired glucose tolerance (IFG/IGT), family history of diabetes mellitus (DM), and medical conditions.

  1 year

Interventions

75 g glucose tolerance test OTHER

Pregnant patient who visited obstetric clinic , who did 75 g glucose tolerance test

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All pregnant patients who attend high risk pregnancy outpatient's clinic at national guard hospital in Jeddah during 2021-2022. Dependent Variable: OGTT - Fasting Blood Glucose - Weight - Pregestational BMI Independent Variable(s): Age, Gender, Medication, Gestational age, Chronic diseases, Family history, Past gyne and medical history.

You may qualify if:

• Singleton pregnant women who received prenatal care services in Obstetrics clinics at king Abdul-Aziz medical city.

You may not qualify if:

• Pregnant known to have diabetes mellitus.
• Participant with Autoimmune disease.

Sponsors & Collaborators

• King Abdulaziz Medical City: lead

Study Sites (1)

Fatimah Khobrani

Jeddah, Saudi Arabia

Location

MeSH Terms

Conditions

Diabetes, Gestational

Interventions

Glucose Tolerance Test

Condition Hierarchy (Ancestors)

Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Blood Chemical Analysis; Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Diagnostic Techniques, Endocrine; Investigative Techniques

Study Officials

• Fatimah M Khobrani, Associate

  KAMC

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate consultant family medicine

Study Record Dates

• First Submitted: October 15, 2023
• First Posted: October 31, 2023
• Study Start: May 23, 2022
• Primary Completion: May 1, 2023
• Study Completion: July 2, 2023
• Last Updated: October 31, 2023

Record last verified: 2023-10

Locations

SA (1)