Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation.
HINDIP
1 other identifier
observational
530
1 country
2
Brief Summary
Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Longer than P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedFirst Submitted
Initial submission to the registry
October 25, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 30, 2023
CompletedFirst Posted
Study publicly available on registry
October 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
October 31, 2023
CompletedNovember 2, 2023
October 1, 2023
7.8 years
October 25, 2023
October 31, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Admission to the hospital
Risk for admission to the hospital
between january 1, 2023 and november 1, 2023
Study Arms (3)
DENGUE INFECTED PATIENTS. YEAR 2016
We conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and december 31, 2016. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
DENGUE INFECTED PATIENTS. YEAR 2020
We conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2020, and december 31, 2020. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
DENGUE INFECTED PATIENTS. YEAR 2023
We conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2023, and november 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
Interventions
hyponatremia at admission in dengue infected patients
Eligibility Criteria
Patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and May 31, 2023.
You may qualify if:
- Diagnosis confirmed by PCR, non structural protein 1 (NS1) antigen or IgM serology.
- Plasma sodium at admission.
You may not qualify if:
- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Ladislao Diaz Ballve
Haedo, Buenos Aires, 1706, Argentina
Hospital Posadas
Buenos Aires, 1684, Argentina
Related Publications (1)
Ayus JC, Negri AL, Moritz ML, Lee KM, Caputo D, Borda ME, Go AS, Eghi C. Hyponatremia, Inflammation at Admission, and Mortality in Hospitalized COVID-19 Patients: A Prospective Cohort Study. Front Med (Lausanne). 2021 Dec 2;8:748364. doi: 10.3389/fmed.2021.748364. eCollection 2021.
PMID: 34926496BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
CARLOS EGHI, MD
HOSPITAL NACIONAL PROF. A. POSADAS
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 8 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
October 25, 2023
First Posted
October 31, 2023
Study Start
January 1, 2016
Primary Completion
October 30, 2023
Study Completion
October 31, 2023
Last Updated
November 2, 2023
Record last verified: 2023-10