Percutaneous Imaging-guided Cryoblation of the Anterior Abdominal Wall Endometriosis Scars

NCT06108167 | Unknown

• 1 other identifier: 8955
• Study Type: observational
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

Endometriosis is a common condition affecting 10% of women. It is characterized by the presence of ectopic endometrial cells. This pathology most frequently develops in the ovaries, utero-sacral ligaments and pelvic peritoneum, but also in the recto-sigmoid. Rarely, these lesions are found outside the pelvis, and even more exceptionally in the abdominal wall (in 0.03 to 1% of cases). Cryotherapy has already been used for many years to treat soft tissue tumors (kidney and prostate tumors). It has also been successfully used by interventional radiologists to treat parietal desmoid tumors. After discussions with radiologists, given the similarity of location and extension of wall endometriosis lesions with desmoid tumours, the successes observed, and the scarcity of studies in the literature, it seemed appropriate to the investigators to study this new therapy. The aim of this study was to investigate the efficacy of cryotherapy on parietal endometriosis lesions.

Conditions

Endometriosis

Keywords

Endometriosis; Endometrial cells; Radiofrequency; Anterior abdominal; Cryotherapy

Outcome Measures

Primary Outcomes (1)

• Efficacy of cryotherapy on parietal endometriosis lesions was assessed using the a visual analogue scale (VAS) ranging from 0 to 10.

  Before and 6 months after the cryotherapy

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult woman (≥18 years old) Having benefited from cryotherapy of an abdominal wall endometriosis nodule between January 6, 2020 and January 2, 2023.

You may qualify if:

• Adult woman (≥18 years old) Having benefited from cryotherapy of an abdominal wall endometriosis nodule between January 6, 2020 and January 2, 2023.
• Subject not objecting to the reuse of their data for the purposes of this research

You may not qualify if:

• Subject having expressed its opposition to the reuse of its data for scientific research purposes.

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Gynécologie Obstétrique - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Endometriosis

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Central Study Contacts

Victor GABRIELE, MD

CONTACT

33 3 69 55 34 04; victor.gabriele@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 28, 2023
• First Posted: October 30, 2023
• Study Start: May 5, 2023
• Primary Completion: November 5, 2023
• Study Completion: November 5, 2023
• Last Updated: November 2, 2023

Record last verified: 2023-08

Locations

FR (1)