Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury

NCT06107556 | Unknown

• 1 other identifier: 2023-A02258-37
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.

Conditions

Stroke; Walking, Difficulty; Spasticity/Paresis

Outcome Measures

Primary Outcomes (1)

• Coefficient of antagonist activation

  The coefficient of antagonist activation of gastrocnemius medialis and soleus was calculated from EMG data by the ratio between the root mean square amplitude during antagonist effort and maximal agonist effort for the same muscle.

  1 year

Interventions

Gait analysis DIAGNOSTIC_TEST

3D gait analysis with electromyographic measurements

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Person with a history of stroke

You may qualify if:

• Adult
• Person who performed tridimensional gait analysis in laboratory
• Person who had a stroke at least 6 months before the gait analysis

You may not qualify if:

• Any other neurological pathology or gait disorders
• Botulinum toxin injection in the last 3 months before the gait analysis

Sponsors & Collaborators

• Henri Mondor University Hospital: lead

Study Sites (1)

Laboratoire Analyse et Restauration du Mouvement

Créteil, France

Location

MeSH Terms

Conditions

Stroke; Mobility Limitation; Muscle Spasticity; Paresis

Interventions

Gait Analysis

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Muscle Hypertonia; Neuromuscular Manifestations; Neurologic Manifestations

Intervention Hierarchy (Ancestors)

Gait; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Physical Functional Performance; Physical Fitness; Health; Population Characteristics

Study Officials

• Emilie Hutin

  Hôpitaux Universitaires Henri Mondor

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Emilie Hutin, Ph.D.

CONTACT

0149812549; emilie.hutin@aphp.fr

Emilie Hutin

CONTACT

0149812549; emilie.hutin@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: October 19, 2023
• First Posted: October 30, 2023
• Study Start: October 19, 2023
• Primary Completion: October 19, 2023
• Study Completion: June 30, 2024
• Last Updated: October 30, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)