NCT06102850

Brief Summary

Young adults experiencing homelessness have high rates of mental health conditions but low rates of service utilization and the point of transition from homelessness to supported housing provides a window of opportunity for intervention. The goal of this study is to adapt the evidenced-based intervention, Critical Time Intervention, for young adults with mental health conditions who are entering a rapid rehousing program and test the adapted intervention in a randomized feasibility pilot trial. Participants in the pilot trial will be asked to participate in the CTI-YAMH intervention that involves structured case management and supports from a mental health liaison and a peer support specialist. After a pilot feasibility phase (n=8), we will test the intervention by randomly assigning young adults on the housing wait list to a housing program with CTI-YAMH (n=26) or to get housing supports from another agency that does not provide CTI-YAMH (treatment as usual, n=26).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 5, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

October 20, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 26, 2023

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2025

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2025

Completed
Last Updated

October 26, 2023

Status Verified

October 1, 2023

Enrollment Period

1.4 years

First QC Date

October 20, 2023

Last Update Submit

October 20, 2023

Conditions

Mental Disorder

Outcome Measures

Primary Outcomes (5)

  • Housing Stability

    Housing Security Scale Number of days homeless, Number of moves in prior 90 days

    Baseline, 3 mo, 6 mo, 12 mo

  • Mental Disorder

    Diagnosis of Common Disorders i.e. Depression, Anxiety, Bipolar, Psychotic Disorders

    Baseline, 12 mo.

  • Depressive Symptoms

    PHQ-9

    Baseline, 3 mo, 6mo, 12 mo.

  • Anxiety Symptoms

    GAD-7

    Baseline, 3 mo, 6mo, 12 mo.

  • PTSD Symptoms

    Primary Care PTSD Screen

    Baseline, 3 mo, 6mo, 12 mo.

Secondary Outcomes (1)

  • Treatment Engagement

    Baseline, 3 mo, 6mo, 12 mo.

Study Arms (2)

Intervention Condition, CTI-YAMH

EXPERIMENTAL

Participants receive the CTI-YAMH intervention in conjunction with rapid rehousing supports for the 6 month intervention

Behavioral: Critical Time Intervention for Young Adults with Mental Health conditions

Treatment as Usual Condition

NO INTERVENTION

Participants will be assigned to a housing program at another agency that provides rapid rehousing with usual supports

Interventions

Critical Time Intervention for Young Adults with Mental Health conditionsBEHAVIORAL

SIx month supportive intervention involving CTI phased based casemanagement, support from a peer support specialist, and support from a mental health liaison

Intervention Condition, CTI-YAMH

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Young adults (age 18-24) on the housing eligibility list assigned to rapid rehousing
  • Positive for psychological distress on Kessler-6 or self-reported prior diagnosis of depression, anxiety, bipolar or a psychotic disorder with ongoing symptoms

You may not qualify if:

  • Age 25 or older
  • Not English speaking
  • No eligible for rapid rehousing based on housing priority score

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Covenant House Texas

Houston, Texas, 77006, United States

RECRUITING

Related Publications (1)

  • Narendorf SC, Munson MR, Khan U, Brown M, Gomez G, Santa Maria D, Gilmer T, Gattis MN, Hayward P, Herman D. Study protocol for a feasibility evaluation of Charge Up!: an adaptation of Critical Time Intervention for young adults moving from homelessness to housing. Pilot Feasibility Stud. 2025 Jul 2;11(1):91. doi: 10.1186/s40814-025-01677-7.

    PMID: 40605122DERIVED

MeSH Terms

Conditions

Mental Disorders

Central Study Contacts

Alicia Vargas

CONTACT

713-743-9215avargas2@uh.edu

Yadira Cortez

CONTACT

713-743-5571ycortez2@central.uh.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: This study includes a phased open trial, first using a single group feasibility pilot (n=8) to refine the intervention manuals, then employed a randomized parallel feasibility pilot (n=26 in each group)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 20, 2023

First Posted

October 26, 2023

Study Start

September 5, 2023

Primary Completion

January 31, 2025

Study Completion

November 30, 2025

Last Updated

October 26, 2023

Record last verified: 2023-10

Data Sharing

IPD Sharing
Will share

Data will be uploaded to the NIMH NDA using GUID identifiers

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
in accordance with data sharing requirements for NIMH
Access Criteria
Institutional level through the NDA
More information

Locations

US(1)