Cohort Study in Fujian Province

NCT06102187 | Recruiting DMC

• 1 other identifier: LYu
• Study Type: observational
• Target: 150,000
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, Chinese residents aged 35 to 75 years old were recruited from Fujian Province. Physical examination, questionnaire survey and biological sample collection were performed at baseline, and at least 4 years of follow-up were conducted. Information on newly discovered cardiovascular metabolic illnesses and comorbidities was collected during follow-up, and repeated surveys similar to baseline were conducted. To explore the relationship between environment, diet and lifestyle and the risk of cardiovascular metabolic diseases and concomitant disorders.

Conditions

Chronic Disease

Keywords

Cardiovascular and metabolic disease comorbidity

Outcome Measures

Primary Outcomes (1)

• Coronary Disease

  It is a form of myocardial ischemia (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. At the follow-up, the outcomes of coronary events were acquired. Coronary CTA examination and coronary angiography were the primary measuring modalities.

  5 years

Secondary Outcomes (1)

• other metabolic diseases

  5 years

Eligibility Criteria

• Age: 35 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 150,000 adult China aged 35 to 74 who have lived in urban or rural areas of Fuzhou, Putian, Quanzhou, Nanping, Xiamen, Zhangzhou, Longyan, Sanming and Ningde in Fujian Province for more than 6 months without cardiovascular disease history and major disability.

You may qualify if:

• Aged 35-75, having lived in Fuzhou, Putian, Quanzhou, Nanping, Xiamen, Zhangzhou, Longyan, Sanming, or Ningde in Fujian Province for more than 6 months.

You may not qualify if:

• Anyone diagnosed with coronary heart disease, stroke, or cancer.
• Anyone with a severe disability who is unable to participate in the study.

Sponsors & Collaborators

• Fujian Provincial Hospital: lead
• Center for Disease Control and Prevention, Fujian: collaborator
• China National Center for Cardiovascular Diseases: collaborator

Study Sites (1)

Fujian Provincial Hospital

Fuzhou, Fujian, 350000, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Blood and Urine samples for biochemical tests, biomarker examination and DNA extraction.

MeSH Terms

Conditions

Chronic Disease

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Kaiyang Lin

CONTACT

+8613559355708; lky7411@sina.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Deputy director

Study Record Dates

• First Submitted: October 22, 2023
• First Posted: October 26, 2023
• Study Start: January 1, 2017
• Primary Completion: December 31, 2025
• Study Completion (Estimated): December 31, 2026
• Last Updated: November 3, 2023

Record last verified: 2023-11

Locations

CN (1)