The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis

NCT06102148 | Completed

• 1 other identifier: 2021/413
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine the effects of PNF techniques on pain, motor function, fatigue and quality of life.

Conditions

Multiple Sclerosis

Keywords

Multiple Sclerosis; Proprioceptive Neuromuscular Facilitation; Pain; Motor Function; Fatigue; Quality of Life

Outcome Measures

Primary Outcomes (6)

• Visual Analogue Scale (VAS)

  Pain

  through study completion, an average of 1 year

• Multiple Sclerosis Quality of Life-54 (MSQoL-54)

  Quality of Life

  through study completion, an average of 1 year

• Fatigue Severity Scale and Fatigue Impact Scale (FIS)

  Fatigue

  through study completion, an average of 1 year

• Timed Up and Go (TUG)

  Mobility and Balance

  through study completion, an average of 1 year

• The Six-Minute Walk Test (6-MWT)

  Functionality

  through study completion, an average of 1 year

• Hand Dexterity

  Hand Dexterity

  through study completion, an average of 1 year

Study Arms (2)

PNF Group

EXPERIMENTAL

Other: PNF Group

Control Group

SHAM COMPARATOR

Other: Control Group

Interventions

PNF Group OTHER

Exercise training and PNF training

PNF Group

Control Group OTHER

Exercise training

Control Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• a clinical diagnosis of Relapsing-Remitting MS (RRMS) as defined by McDonald criteria
• years of age
• an Expanded Disability Status Scale (EDSS) score \< 4
• relapse-free for the last 3 months
• cognitive impairment that was defined with mini mental test.

You may not qualify if:

• a history of different neurological diseases
• having any contraindication for exercise
• having orthopedic, vision, hearing, or perception problems.

Sponsors & Collaborators

• Nilay Comuk Balci: lead

Study Sites (1)

Ondokuz Mayıs University

Samsun, 55270, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis; Pain; Fatigue

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: October 16, 2023
• First Posted: October 26, 2023
• Study Start: November 1, 2021
• Primary Completion: November 1, 2022
• Study Completion: November 1, 2022
• Last Updated: October 26, 2023

Record last verified: 2023-10

Locations

TU (1)