A Comparative Study Between Ultrasound Guided External Oblique Intercostal Plane (EOIP) Block and Erector Spinae Plane (ESP) Block for Postoperative Analgesia in Upper Abdominal Surgeries

NCT06097286 | Unknown

• 1 other identifier: MD80/2023
• Study Type: interventional
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

Upper abdominal incisions, such as the oblique subcostal laparotomy, can cause severe pain and can lead to significant respiratory impairment. Erector spinae plane (ESP) block is the deposition of local anaesthetic (LA) in the interfascial plane at the paraspinal region. It provides effective visceral and somatic analgesia. External oblique intercostal plane (EOIP) block is a newly described block at which local anaesthetic (LA) is deposited in the interfascial plane deep to external oblique muscle at the sixth intercostal space. It provides blockade of the thoracoabdominal nerves at the level of T6 to T10. In this study, the investigators compare between ultrasound (US) guided external oblique intercostal plane block and erector spinae plane block, in providing postoperative analgesia for upper abdominal surgeries

Conditions

Block

Outcome Measures

Primary Outcomes (1)

• amount of total 24 hour pethidine consumption (mg) .

  to measure total 24 hour pethidine consumption postoperatively.

  24 hours postoperatively

Secondary Outcomes (5)

• visual analogue scale (VAS) at rest and movement.

  24 hours postoperatively

• mean arterial blood pressure (MAP)

  24 hours postoperatively

• heart rate (HR)

  24 hours postoperatively

• incidence of postoperative complications (nausea and vomiting)

  24 hours postoperatively

• time to start mobilization

  24 hours postoperatively

Study Arms (3)

external oblique intercostal plane block

ACTIVE COMPARATOR

Procedure: external oblique intercostal plane block

erector spinae plane block

ACTIVE COMPARATOR

Procedure: erector spinae plane block

control group

NO INTERVENTION

Interventions

external oblique intercostal plane block PROCEDURE

o EOIP Group (ŋ=25): Patients will receive ultrasound guided External oblique intercostal plane block with 20 ml of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a total volume of 20 ml.) at the end of procedure, unilaterally or bilaterally according to the surgery.

external oblique intercostal plane block

erector spinae plane block PROCEDURE

o ESP Group (ŋ=25): Patients will receive ultrasound guided Erector spinae plane block with 20 ml of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a total volume of 20 ml.) at the end of procedure, unilaterally or bilaterally according to the surgery.

erector spinae plane block

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with American Society of Anesthesiologists physical status (ASA) I and II.
• Both sex.
• to 60 years old patients.
• upper abdominal surgeries.

You may not qualify if:

• Refusal of the patient to consent.
• Patients with ASA status III or IV
• Patients with bleeding disorders and coagulopathy (INR≥1.6 \& PTT≥50 sec).
• Infection at the injection site.
• Allergy to local anesthetics.
• Patients with ages less than 20 or more than 60
• Patients with pre-existing myopathy or neuropathy.
• Patients with chronic pain syndromes.
• Patients with history of long acting opioids or steroids preoperatively.

Sponsors & Collaborators

• Ain Shams University: lead

MeSH Terms

Conditions

Bites and Stings

Condition Hierarchy (Ancestors)

Poisoning; Chemically-Induced Disorders; Wounds and Injuries

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 21, 2023
• First Posted: October 24, 2023
• Study Start: November 1, 2023
• Primary Completion: April 1, 2024
• Study Completion: June 1, 2024
• Last Updated: October 24, 2023

Record last verified: 2023-03