NCT06088641

Brief Summary

The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
198

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2023

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

October 6, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 18, 2023

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 6, 2024

Completed
Last Updated

November 18, 2023

Status Verified

November 1, 2023

Enrollment Period

1.2 years

First QC Date

October 6, 2023

Last Update Submit

November 15, 2023

Conditions

Myocardial Injury After Non-cardiac Surgery

Keywords

AAAMINSBNP

Outcome Measures

Primary Outcomes (1)

  • MINS

    MINS is defined as an elevated Troponin-T within 30 days of surgery. The patients were divided into two groups based on their preoperative BNP levels, and the incidence of MINS was compared between the two groups.

    30 days after surgery

Study Arms (2)

Lower BNP

preoperative Lower BNP

Diagnostic Test: preoperative BNP value

Higher BNP

preoperative higher BNP

Diagnostic Test: preoperative BNP value

Interventions

preoperative BNP valueDIAGNOSTIC_TEST

preoperative BNP value

Higher BNPLower BNP

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients who underwent AAA open repair

You may qualify if:

  • patients who underwent open repair with AAA from September 2010 to October 2021

You may not qualify if:

  • Ruptured AAA
  • Traumatic aortic injury
  • Absence of troponin-T value within 30 days of surgery
  • Diagnosis of elevation of troponin-T due to non-ischemic cause (ex: sepsis, pulmonary embolism, atrial fibrillation, cardioversion, etc.)
  • Insufficient medical records

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gangnam severance Hospital

Seoul, South Korea

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

October 6, 2023

First Posted

October 18, 2023

Study Start

January 1, 2022

Primary Completion

March 30, 2023

Study Completion

July 6, 2024

Last Updated

November 18, 2023

Record last verified: 2023-11

Locations

KR(1)