Olfactory Cleft Stenosis and Obstruction on Paranasal Sinus CT Scan in Pre Septo Rhinoplasty Patients Without Respiratory Mucosa Pathology : Normal Variants or Pathologic Findings ?

NCT06082193 | Unknown DMC

• 1 other identifier: 2023PI023
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 2

Brief Summary

This retrospective studed included patients referred to our institution between December 2013 and december 2021 for septoplasty or septorhinoplasty. All patients underwent pre operatory paranasal sinus CT scan and olfactory test. Olfacory cleft stenosis will be quoted as none (less than 1/3 contact between nasal septum and ethmoïd turbinates), partial (1/3-2/3 contact between nasal septum and turbinates) or total (more than 2/3 contact between nasal septum and turbinates), as well as Olfactory Cleft obstruction as none (opacification less than 1/3 of olfactory cleft), partial (1/3-2/3 opacification) or complete (more than 2/3 opacification).

Conditions

Olfactory Impairment

Keywords

Olfactory Cleft stenosis; Sniffin stick test; Non mucosa pathology; Olfactory recess; Olfactory Cleft Obstruction; Olfactory normal variant

Outcome Measures

Primary Outcomes (1)

• Olfactory cleft stenosis or obstruction

  Measures will classify as none, partial or total stenosis or obstruction

  1 day

Secondary Outcomes (1)

• Impact of olfactory cleft stenosis or obstruction

  1 day

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

\- Patients over 18 years old who underwent paranasal sinus CT and olfactory test before septoplasty or septorhinoplasty without respiratory mucosa pathology Sex, mean age Olfactory test threshold and identification using sniffin stick test. Classification normosmic or hyposmic using Hummel table.

You may qualify if:

• Patients over 18 years old who underwent paranasal sinus CT and olfactory test before septoplasty or septorhinoplasty

You may not qualify if:

• Respiratory mucosa pathology on CT (polyposis, opacification of the maxillary sinuses, ethmoid cells, frontal sinus, sphenoidal sinus, sinonasal tumor)
• septal perforation
• chronic respiratory rhinitis (allergic, vasomotor, mucoviscidosis)
• pathologie that can alter olfaction (multiple sclerosis, meningioma, post infection such as COVID)

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (2)

Jankowski Roger

Nancy, 54000, France

RECRUITING

Centre Hospitalier Régional Universitaire - Service ORL

Nancy, France

RECRUITING

Related Publications (23)

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• Lima NB, Jankowski R, Georgel T, Grignon B, Guillemin F, Vignaud JM. Respiratory adenomatoid hamartoma must be suspected on CT-scan enlargement of the olfactory clefts. Rhinology. 2006 Dec;44(4):264-9.

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MeSH Terms

Conditions

Olfaction Disorders

Condition Hierarchy (Ancestors)

Sensation Disorders; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: October 8, 2023
• First Posted: October 13, 2023
• Study Start: August 1, 2023
• Primary Completion: October 8, 2023
• Study Completion: October 25, 2023
• Last Updated: October 13, 2023

Record last verified: 2023-10

Locations

FR (2)