Endovascular Treatment for AIS in Chinese Municipal and County Hospitals： A "Real World" Study-ETERNITY Registry

NCT06078917 | Completed DMC

• 1 other identifier: A "Real world" study-ETERNITY
• Study Type: observational
• Target: 1,196
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the Endovascular Treatment difference between Chinese city and country hospital.

Conditions

Endovascular Treatment

Keywords

Endovascular Treatment; acute ischemic stroke

Outcome Measures

Primary Outcomes (3)

• The modified Rankin Scale score at 90 days

  The range of the modified Rankin Scale is from 0 to 6. A higher score indicates a worse outcome. 0-No symptoms; 1-No significant disability; 2-Slight disability; 3-Moderate disability; 4-Moderately severe disability; 5-Severe disability; 6-Dead.

  90 days

• Baseline CT/magnetic resonance and CT angiography/magnetic resonance angiography imaging, digital subtraction angiography

  Radiological assessment included ASPECTS ，location of occlusion site, presence of underlying ICAS ，or exist microcatheter "First-Pass Effect".

  90 days

• Successful reperfusion

  Successful reperfusion was defined as eTICI ≥2b

  90 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with acute ischemic stroke caused by anterior circulation intracranial large vessel occlusion and receiving EVT were included.

You may qualify if:

• (1) age ≥18 years; (2) diagnosis of AIS caused by imaging-confirmed intracranial LVO, including isolated cervical internal carotid artery or tandem occlusion, intracranial internal carotid artery, middle cerebral artery (M1/M2), anterior cerebral artery (A1/A2); (3) initiation of any type of EVT, including mechanical thrombectomy, emergent angioplasty via balloon or/and stent; (4).Onset-to-presentation time with 24 hours; (5).Patients whose onset-to-presentation time surpass 6 hours should had CTP and fulfill with DAWN\[6\] or DEFUSE's\[7\] criteria.

You may not qualify if:

• (1) Without follow up outcome; (2) posterior circulation stroke;(3)no evidence of LVO on angiogram.

Sponsors & Collaborators

• Wen-huo Chen: lead

Study Sites (1)

Zhangzhou Municipal Hospital

Zhangzhou, Fujian, 363000, China

Location

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Wen-huo Chen, bachelor

  Zhangzhou Affiliated Hospital to Fujian Medical University , Fujian ,China

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 90 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Endovascular Treatment for Acute Ischemic Stroke in Chinese Municipal and County Hospitals： A "Real World" Study-ETERNITY Registry

Study Record Dates

• First Submitted: October 5, 2023
• First Posted: October 12, 2023
• Study Start: November 1, 2021
• Primary Completion: December 31, 2022
• Study Completion: July 31, 2023
• Last Updated: October 12, 2023

Record last verified: 2023-10

Locations

CN (1)