NCT05988125

Brief Summary

To investigate the real situation of assessment, diagnosis and treatment of acute ischemic stroke patients with endovascular therapy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
2,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2017

Longer than P75 for all trials

Geographic Reach
1 country

6 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
6.6 years until next milestone

First Submitted

Initial submission to the registry

August 4, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

August 14, 2023

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2025

Completed
Last Updated

October 8, 2024

Status Verified

January 1, 2024

Enrollment Period

8 years

First QC Date

August 4, 2023

Last Update Submit

October 4, 2024

Conditions

Keywords

acute Ischemic StrokeEndovascular Treatment

Outcome Measures

Primary Outcomes (1)

  • The modified Rankin Scale score at 90 days

    The range of the modified Rankin Scale is from 0 to 6. A higher score indicates a worse outcome. 0-No symptoms; 1-No significant disability; 2-Slight disability; 3-Moderate disability; 4-Moderately severe disability; 5-Severe disability; 6-Dead.

    90 days

Secondary Outcomes (2)

  • Successful reperfusion rate

    90 days

  • symptomatic intracranial hemorrhage or death within 90 days after stroke onset.

    90 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Acute ischemic stroke patients receiving endovascular treatment.

You may qualify if:

  • Acute ischemic stroke;
  • Brain imaging confirmed intracranial large vessel occlusion: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA V4), and posterior cerebral artery (PCA P1);
  • Initiation of any type of endovascular treatment, including mechanical thrombectomy, aspiration, angioplasty, and stenting;
  • Informed Consent as documented by signature or fulfilling the criteria for emergency consent/ deferral consent

You may not qualify if:

  • Acute intracranial haemorrhage
  • No evidence of large vessel occlusion on digital subtraction angiography.
  • Patient bedridden or presenting from a nursing home
  • Foreseeable difficulties in follow-up due to geographic reasons (e.g. patients living abroad) -

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Zhangzhou Municipal Hospital

Zhangzhou, Fujian, 36300, China

RECRUITING

Gansu provincial hospital of TCM

Lanzhou, Gansu, 730050, China

RECRUITING

Jiamusi Central Hospital

Jiamusi, Heilongjiang, 154000, China

RECRUITING

Department of Neurology, The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330006, China

RECRUITING

Songyuan Jilin Oilfield Hospital

Songyuan, Jilin, 138000, China

RECRUITING

Shenyang First People's Hospital

Shenyang, Liaoning, 110091, China

RECRUITING

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Wen-huo Chen, bachelor

    Zhangzhou Affiliated Hospital to Fujian Medical University , Fujian ,China

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Wen-huo Chen, bachelor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
90 Days
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Prospective Registry Study of Endovascular Treatment for Acute Ischemic Stroke Patients in China

Study Record Dates

First Submitted

August 4, 2023

First Posted

August 14, 2023

Study Start

January 1, 2017

Primary Completion

December 31, 2024

Study Completion

March 31, 2025

Last Updated

October 8, 2024

Record last verified: 2024-01

Locations