Postoperative Analgesia After Total Hip Arthroplasty: Comparative Evaluation of Pericapsular Nerve Group Versus Fascia Iliaca Compartment Block

NCT06003738 | Completed

• 1 other identifier: FMASU MD76/2023
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare the effectiveness of pericapsular nerve group (PENG) block versus fascia iliaca compartment block (FICB) for postoperative pain relief following total hip arthroplasty (THA).

Conditions

Postoperative Analgesia; Total Hip Arthroplasty; Pericapsular Nerve Group Block; Fascia Iliaca Compartment Block

Outcome Measures

Primary Outcomes (3)

• Degree of pain

  Degree of pain was assessed using the Visual Analogue Scale (VAS). VAS is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain. VAS was recorded at 0, 2, 4, 6, 12, 18, and 24 hours postoperatively.

  24 hours postoperatively

• Total amount of nalbuphine consumption

  If the postoperative Visual Analogue Scale (VAS) was greater than 3, an intravenous dose of 5 mg Nalbuphine diluted in 5 mL of saline was administered as needed.

  24 hours postoperatively

• Number of cases needing rescue doses

  The number of cases needing rescue doses was recorded.

  24 hours postoperatively

Secondary Outcomes (1)

• Postoperative ambulation

  24 hours postoperatively

Study Arms (2)

Group A

EXPERIMENTAL

Patients received an ultrasound-guided supra-inguinal fascia iliaca compartment block.

Other: Fascia iliaca compartment block

Group B

ACTIVE COMPARATOR

Patients received an ultrasound-guided pericapsular nerve group (PENG) block.

Other: Pericapsular nerve group block

Interventions

Fascia iliaca compartment block OTHER

Patients received an ultrasound-guided supra-inguinal fascia iliaca compartment block.

Group A

Pericapsular nerve group block OTHER

Patients received an ultrasound-guided pericapsular nerve group (PENG) block.

Group B

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age from 18 to 80 years.
• Both sexes.
• American Society of Anaesthesiologists (ASA) Physical Status II-III.
• Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

You may not qualify if:

• Patients' refusal
• Contraindications to spinal anesthesia or nerve blocks.
• History of allergy to the medications used in the study.
• Pregnancy.
• Significant cognitive impairment.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain shams University

Cairo, 11588, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesia

Study Record Dates

• First Submitted: July 12, 2023
• First Posted: August 22, 2023
• Study Start: September 1, 2023
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: August 13, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)