Early Detection of Lung Cancer In Patients With Chronic Chest Diseases
Radiological Early Detection of Lung Cancer In Patients With Chronic Chest Diseases.
1 other identifier
observational
100
0 countries
N/A
Brief Summary
- To evaluate the effectiveness of LDCT in detecting early-stage lung cancer in patients with chronic lung conditions compared to standard chest x-rays.
- To improve lung cancer outcomes through optimized use of radiological technologies for early detection in high-risk patients with pre-existing lung conditions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2023
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 1, 2023
CompletedFirst Posted
Study publicly available on registry
October 10, 2023
CompletedStudy Start
First participant enrolled
December 20, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 20, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 20, 2024
CompletedNovember 7, 2023
October 1, 2023
10 months
October 1, 2023
November 3, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Detection early-stage lung cancer (Stage I/II) • Lung • Lung cancer mortality rate
By LDCT
baseline
Secondary Outcomes (1)
• Diagnostic accuracy of imaging modalities • Positive predictive value of screening tests • Rate of unnecessary invasive procedures • Identification of high-risk subgroups
baseline
Eligibility Criteria
After taking the informed consent, full history was taken from all patients participating in the study. Detailed clinical examination and routine laboratory investigations (complete blood count, liver function test, urea, creatinine and ESR) will be done. * Radiological imaging technologies -Low Dose Computed tomography (CT scans), chest x-rays These are used to detect and characterize lung abnormalities. * Pulmonary function tests - Spirometry volume measurements, diffusion capacity testing. These assess lung health and function in patients with chronic lung conditions
You may qualify if:
- Chronic chest diseases Patients .
You may not qualify if:
- Age: less than 45 years. 2-Patients diagnosed with lung cancer 3-Unstable patients or need for ICU admission
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Balkan A, Bulut Y, Fuhrman CR, Fisher SN, Wilson DO, Weissfeld JL, Sciurba FC. COPD phenotypes in a lung cancer screening population. Clin Respir J. 2016 Jan;10(1):48-53. doi: 10.1111/crj.12180. Epub 2014 Jul 28.
PMID: 24989058BACKGROUNDJogi J, Markstad H, Tufvesson E, Bjermer L, Bajc M. The added value of hybrid ventilation/perfusion SPECT/CT in patients with stable COPD or apparently healthy smokers. Cancer-suspected CT findings in the lungs are common when hybrid imaging is used. Int J Chron Obstruct Pulmon Dis. 2014 Dec 18;10:25-30. doi: 10.2147/COPD.S73423. eCollection 2015.
PMID: 25565797BACKGROUND
Study Officials
- STUDY CHAIR
Mustafa sayed, lecture
Assiut University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecture of chest diseases
Study Record Dates
First Submitted
October 1, 2023
First Posted
October 10, 2023
Study Start
December 20, 2023
Primary Completion
October 20, 2024
Study Completion
December 20, 2024
Last Updated
November 7, 2023
Record last verified: 2023-10