Follow up After TACE by Elastography and Color Doppler.

NCT06070623 | Unknown

• 1 other identifier: Elastography, Doppler in TACE.
• Study Type: observational
• Target: 54
• Locations: 0 countries
• Sites: N/A

Brief Summary

To determine accuracy of elastography and color Doppler in follow up of patients with HCC after TACE comparing with modified RECIST criteria.

Conditions

Hepatocellular Carcinoma

Keywords

TACE

Outcome Measures

Primary Outcomes (1)

• Role of elastography and color Doppler to follow up after TACE.

  Accuracy of elastography and color Doppler in follow up of patients with HCC who underwent TACE, compared to modified RECIST criteria.

  Baseline

Interventions

US DEVICE

We use elastography and color Doppler from US machine and compare results with CT

Also known as: CT

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with hepatic focal lesion , which is eligable to trans arterial chemoebmolization.

You may qualify if:

• All patients with hepatocellular carcinoma underwent TACE in South Egypt cancer institute.

You may not qualify if:

• Patients with liver metastases.
• Patients with hepatic or perihepatic inflammations.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Tierney J, Baker J, Borgmann A, Brown D, Byram B. Non-contrast power Doppler ultrasound imaging for early assessment of trans-arterial chemoembolization of liver tumors. Sci Rep. 2019 Sep 10;9(1):13020. doi: 10.1038/s41598-019-49448-8.

  PMID: 31506503 BACKGROUND

• Sato Y, Watanabe H, Sone M, Onaya H, Sakamoto N, Osuga K, Takahashi M, Arai Y; Japan Interventional Radiology in Oncology Study Group-JIVROSG. Tumor response evaluation criteria for HCC (hepatocellular carcinoma) treated using TACE (transcatheter arterial chemoembolization): RECIST (response evaluation criteria in solid tumors) version 1.1 and mRECIST (modified RECIST): JIVROSG-0602. Ups J Med Sci. 2013 Mar;118(1):16-22. doi: 10.3109/03009734.2012.729104. Epub 2012 Nov 20.

  PMID: 23167460 BACKGROUND

• Hou S, Hua S, Cui K, Liu F, Ding K, Yuan J. The course and prognostic value of tumor stiffness detected by ultrasound elastography for transarterial chemoembolization of hepatocellular carcinoma. Quant Imaging Med Surg. 2023 Jun 1;13(6):3962-3972. doi: 10.21037/qims-22-292. Epub 2023 May 9.

  PMID: 37284088 BACKGROUND

• Conti CB, Cavalcoli F, Fraquelli M, Conte D, Massironi S. Ultrasound elastographic techniques in focal liver lesions. World J Gastroenterol. 2016 Mar 7;22(9):2647-56. doi: 10.3748/wjg.v22.i9.2647.

  PMID: 26973405 BACKGROUND

MeSH Terms

Conditions

Carcinoma, Hepatocellular

Condition Hierarchy (Ancestors)

Adenocarcinoma; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Liver Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Digestive System Diseases; Liver Diseases

Study Officials

• Mostafa Thabet, Prof Dr

  Professor doctor at radiology department - Assiut University

  STUDY DIRECTOR

• Haysam Samy, Prof Dr

  Professor doctor at radiology department - South Egypt cancer institute

  STUDY DIRECTOR

• Mohamed Elbaroudy, Ass. Prof Dr

  Assistant professor doctor at radiology department - South Egypt cancer institute

  STUDY DIRECTOR

Central Study Contacts

Marco Drota, Radiologist

CONTACT

+201060134725; marco.moheb279@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr at diagnostic and interventional radiology department - South Egypt cancer institute

Study Record Dates

• First Submitted: October 2, 2023
• First Posted: October 6, 2023
• Study Start: November 1, 2023
• Primary Completion: November 30, 2025
• Study Completion: December 31, 2025
• Last Updated: October 6, 2023

Record last verified: 2023-10