Surgical Intervention and Lymphatic Diseases.
Surgical Intervention and Post Operative Improvement in Patients With Lymphatic Diseases.
1 other identifier
observational
83
1 country
1
Brief Summary
Supermicrosurgical LVA has been proven effective in treating moderate to severe lymphedema, including cases with diffuse dermal backflow (DB) and even severe lymphatic fluid leakage. Therefore, the use of LVA should not be limited to mild lymphedema, and its indications should be expanded to become a primary surgical approach for more severe lymphedema cases. Among all surgical procedures for lymphedema, LVA is the least invasive, allowing for rapid recovery, minimizing the complications, and reducing medical costs.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Sep 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 23, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 10, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2023
CompletedFirst Submitted
Initial submission to the registry
September 28, 2023
CompletedFirst Posted
Study publicly available on registry
October 5, 2023
CompletedOctober 5, 2023
September 1, 2023
6 months
September 28, 2023
September 28, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Volume change after LVA.
The primary endpoint was the volume change at 6/12 months after LVA.
6/12 months
Study Arms (1)
Lower Limb Lymphedema
This was a retrospective cohort propensity score-matched study. Patients with cancer-related unilateral lower limb lymphedema were enrolled.
Interventions
This group included patients who have used only contraction type LVs.
This group included patients who had only non- contraction type LVs.
Eligibility Criteria
All adult patients (age \>20 years) receiving LVA for gynecologic cancer-related unilateral lower limb lymphedema at a tertiary medical center were retrospectively reviewed from October 2015 to July 2022.
You may qualify if:
- This study including patients diagnosed with lymphatic-related diseases at Kaohsiung Chang Gung Memorial Hospital from September 1, 2015, to August 31, 2022.
You may not qualify if:
- Patients under the age of 20.
- Patients with incomplete medical records.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 83301, Taiwan
Related Publications (1)
Knoz M, Wang YM, Luo SD, Wu SC, Lin WC, Tsai PY, Chien PC, Hsieh CH, Yang JC. Comparison of contraction-type and noncontraction-type lymphatic vessels in lymphaticovenous anastomosis for cancer-related unilateral lower limb lymphedema: a retrospective cohort propensity-score-matched outcome analysis. Int J Surg. 2024 Apr 1;110(4):1913-1918. doi: 10.1097/JS9.0000000000001106.
PMID: 38265436DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 28, 2023
First Posted
October 5, 2023
Study Start
September 23, 2022
Primary Completion
March 10, 2023
Study Completion
September 1, 2023
Last Updated
October 5, 2023
Record last verified: 2023-09