Effect of Laser Puncture on Liver Enzymes Post Burn

NCT05728450 | Completed DMC

• 1 other identifier: P.T.REC/012/004203
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Procedures of laser puncture:

• The treatment procedures will start after the patient's release from the intensive care unit.
• The patient will be in a comfortable position.
• The patient will wear protective eyeglasses.
• The points for the application of laser acupuncture will be cleaned before application. All patients in the study group will be submitted to an infrared diode laser, wavelength 808 nm, Pulse duration: 200 ms, Power density: 0.4 W/cm2, energy density 4 J/cm2.
• The plug of the laser unit will be inserted into the main current supply and the on/off switch will be switched on. The therapy form will be selected from the main menu and then the parameters will be set.
• Acupuncture detector (Pointer Excel II) will be used for the definite location of acupuncture points.
• Laser probe will be placed in contact with the skin perpendicular over the body acupoints Zusanli (ST36), Taichong (LR3), Tanyinjiao (SP6), Ganshu (BL18), Yan-glingquan (GB34) and Zhongwan (RN12) in both sides, with a duration of 90 sec for each point three times per week for a month.

Conditions

Burns

Outcome Measures

Primary Outcomes (1)

• EFFECT OF LASER PUNCTURE ON LIVER ENZYMES POST BURN.

  liver enzymes level (AST and ALT enzymes)

  one month

Study Arms (2)

Study group

EXPERIMENTAL

This group includes 15 burned patients who will receive laser puncture for one month (3 times/week) in addition to their physical therapy program (splinting, stretching ex. and ROM ex.) and medical treatment.

Device: Light amplification by stimulated emission of radiation (LASER)

Control group

NO INTERVENTION

This group includes 15 burned patients who will receive their physical therapy program (splinting, stretching ex., strengthening ex. and ROM ex.) and medical treatment.

Interventions

Light amplification by stimulated emission of radiation (LASER) DEVICE

* The points for application of laser acupuncture will be cleaned before application. All patients in the study group will be submitted to infrared diode laser, wavelength 808 nm, Pulse duration: 200 ms, Power density: 0.4 W/cm2, energy density 4 J/cm2 (Chow, 2001). * The plug of the laser unit will inserted into the main current supply and on/off switch will be switched on. The therapy form will be selected from the main menu and then the parameters will be set. * Acupuncture detector (Pointer Excel II) will be used for definite location of acupuncture points

Study group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• The subject selection will be according to the following criteria:
• Age ranges between 20-45 years.
• Male and female patients will participate in the study.
• All patients who have burned with BBSA about 30% to 50% with acupoints are unaffected.
• All patients enrolled on the study will have their informed consent.

You may not qualify if:

• The potential participants will be excluded if they meet one of the following criteria:
• Burn at areas of acupuncture points.
• Lower limb amputation.
• History of liver diseases.
• Body mass index (BMI=kg/cm2)\<30%.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of physical therapy of surgery

Model Details: * The points for applying laser acupuncture will be cleaned before application. All patients in the study group will be submitted to an infrared diode laser, wavelength 808 nm, Pulse duration: 200 ms, Power density: 0.4 W/cm2, energy density 4 J/cm2 (Chow, 2001). * The plug of the laser unit will be inserted into the main current supply and the on/off switch will be switched on. The therapy form will be selected from the main menu and then the parameters will be set. * Acupuncture detector (Pointer Excel II) will be used for the actual location of acupuncture points.

Study Record Dates

• First Submitted: January 19, 2023
• First Posted: February 15, 2023
• Study Start: February 19, 2023
• Primary Completion: March 19, 2023
• Study Completion: April 19, 2023
• Last Updated: August 11, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)