BE Intervention for Naloxone Uptake

NCT06064981 | Completed

• 1 other identifier: 831618
• Study Type: interventional
• Target: 137
• Locations: 1 country
• Sites: 2

Brief Summary

The overall objective of this study is to use behavioral economics interventions to increase naloxone acquisition and carrying among participants who attend an opioid overdose reversal training.

Conditions

Harm Reduction

Outcome Measures

Primary Outcomes (1)

• Naloxone carrying

  Assessed by photo documentation via text message.

  Proportion of successful naloxone check-ins at 14 random time points over a 4 week period post-intervention.

Study Arms (3)

Control

NO INTERVENTION

Participants in the control arm receive usual care. In this case they receive naloxone training only. The training involves a 1-hour in-person overdose recognition and reversal course, which addressed the following topics: the scope and nature of the opioid overdose epidemic nationally and locally in Philadelphia, signs of opioid overdose, strategies for approaching or interacting with a person who is suspected to have overdosed, administration of naloxone in its nasal spray formulation, what to expect after administering naloxone, legal considerations and Good Samaritan protection, and how and where to acquire naloxone.

Text message nudges

EXPERIMENTAL

Participants in this arm receive text message nudges with salient messaging around overdose and naloxone. They also receive naloxone training.

Behavioral: Text message nudges

Commitment contract

EXPERIMENTAL

Participants in this arm receive sign a commitment contract agreeing to obtain or carry naloxone. They also receive naloxone training.

Behavioral: Commitment contract

Interventions

Text message nudges BEHAVIORAL

Fourteen text message "nudges," tailored to address specific barriers and concerns regarding naloxone acquisition and carrying. These barriers were identified using qualitative interviews conducted by the authors in prior studies. Examples included: optimism bias (e.g., beliefs that participants were unlikely to encounter someone who had overdosed in their daily lives), and identity bias (e.g., beliefs that participants were not the type of people who could save a life).

Text message nudges

Commitment contract BEHAVIORAL

In addition to the training, participants in the third arm were asked to sign commitment contracts, which had language in which they "committed" to carrying/acquiring naloxone.

Commitment contract

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Living in the Philadelphia area
• Attended the study naloxone training.

You may not qualify if:

• Unable to consent

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (2)

University of Pennsylvania Health System

Philadelphia, Pennsylvania, 19104, United States

Location

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Harm Reduction

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Carolyn Cannuscio

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: September 26, 2023
• First Posted: October 3, 2023
• Study Start: February 1, 2019
• Primary Completion: August 30, 2019
• Study Completion: December 29, 2019
• Last Updated: January 5, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)