NCT06057480

Brief Summary

Study to evaluate the use of the Assisted Programming Module (APM) in the Evoke Spinal Cord Stimulation (SCS) System to program patients with chronic pain of the trunk and/or limbs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable chronic-pain

Timeline
Completed

Started Sep 2023

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 15, 2023

Completed
11 days until next milestone

Study Start

First participant enrolled

September 26, 2023

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 28, 2023

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 19, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 19, 2024

Completed
Last Updated

May 15, 2025

Status Verified

May 1, 2025

Enrollment Period

1.2 years

First QC Date

September 15, 2023

Last Update Submit

May 12, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in Evoked Compound Action Potentials (ECAPs) measured in µV by the Evoke SCS System

    Change in Evoked Compound Action Potentials (ECAPs) measured in µV by the Evoke SCS System

    end of trial period; 1 month and 3 months post-implant

  • Change in programming parameters (e.g., stimulation frequency [Hz], pulse width [µs], amplitude [mA]) measured by the Evoke SCS System

    Change in programming parameters (e.g., stimulation frequency \[Hz\], pulse width \[µs\], amplitude \[mA\]) measured by the Evoke SCS System

    end of trial period; 1 month and 3 months post-implant

Study Arms (1)

APM

EXPERIMENTAL

Investigational programming software module, the Assisted Programming Module (APM)

Device: APM

Interventions

APMDEVICE

Investigational programming software module, the Assisted Programming Module (APM)

APM

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject has or is planning to undergo a temporary trial with Evoke System within the FDA approved indication.
  • Subject is willing and capable of giving informed consent and able to comply with study-related requirements.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States

Location

Pacific Research Institute

Santa Rosa, California, 95403, United States

Location

The Orthopaedic Institute, PA

Gainesville, Florida, 32607, United States

Location

Center for Clinical Research

Winston-Salem, North Carolina, 27103, United States

Location

Related Publications (1)

  • Parker DJ, Antony AB, Smith GL, Goree JH, Russo MA, Petersen EA, Vu CM, Verrills P, Gilmore C, Kapural L, Nanavati D, Karantonis DM, Pope JE. Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience. Pain Ther. 2026 Jan 8. doi: 10.1007/s40122-025-00808-5. Online ahead of print.

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2023

First Posted

September 28, 2023

Study Start

September 26, 2023

Primary Completion

December 19, 2024

Study Completion

December 19, 2024

Last Updated

May 15, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations