NCT06056531

Brief Summary

Aim: The primary objective was to assess the effect of three different teaching techniques on the success of first-time peripheral intravenous cannulation (PVC) insertion as well as the vein prominence of nursing students. As a secondary objective, the authors conducted research on the students' PVC knowledge levels and skills performance, in the PVC procedure and the duration of the procedure, their satisfaction, and self-confidence in learning. Design: A randomized controlled trial with a pretest and posttest was conducted between February and July 2022, with near-infrared light visualization (n=49), isometric exercise (n=50), and each other's arms (n=48) with nursing students in Turkey.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
147

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2022

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

September 14, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

September 28, 2023

Completed
Last Updated

September 28, 2023

Status Verified

September 1, 2023

Enrollment Period

6 months

First QC Date

September 14, 2023

Last Update Submit

September 20, 2023

Conditions

Keywords

peripheral intravenous cannulationinfrared lightisometric exercise

Outcome Measures

Primary Outcomes (2)

  • Prominence of the selected vein (image)

    Prominence of the vein: 1st degree : veins not visible or palpable, 2nd degree : veins visible but not palpable, 3rd degree : veins barely visible and palpable, 4th degree : veins visible and palpable, 5th degree : veins clearly visible and easily palpable.

    6 months

  • Knowledge, attitude, practice

    A higher total test score was interpreted as a higher level of PVC knowledge. According to the test score, which was between 0 and 40 points, a higher total test score in the assessment demonstrated that the student's PVC skills level was high.

    6 months

Study Arms (3)

NIR light visualization

EXPERIMENTAL

The participant performing PVC carried out the procedure on the arm vein of another volunteer classmate with the help of vein imaging by NIR. All interventions were conducted under the observation of the researchers. The researchers used a chronometer to measure and record how long the PVC took. Participants were asked about the degree of vein prominence under NIR light after the tourniquet was applied, using inspection and palpation. The chronometer was started after the tourniquet was applied and stopped when the catheter plaster was applied. The time that it took to choose the materials needed for the PVC was not added to this time. The researchers recorded whether the PVC procedure was successful or unsuccessful. The cannula's placement during PVC was evaluated by drawing blood and returning it to the vein with a syringe. The PVC procedure was considered a failure if the vein was not opened or no blood reached the syringe.

Other: Near infrared light imaging

isometric hand exercise

EXPERIMENTAL

In this group, the participants performing PVC carried out the procedure by observing vein dilation after isometric exercise. Before the procedure, the students on whom PVC was to be performed were given two stress balls, and they were told how to use them for 15 minutes. The stress balls used in the study were 6 cm in diameter and yellow in color. They were of medium hardness and made of high-quality silicone. The participants were told to squeeze and relax the stress ball in the palm of their hands after counting from one to three, to continue doing this until the procedure began, and to concentrate on squeezing the ball. Participants were asked about the degree of vein prominence after the isometric exercise and tourniquet was applied, using inspection and palpation. The remaining stages were carried out in the same way as with all of the groups.

Other: Isometric exercise with stress ball

Control group: no intervention

NO INTERVENTION

The students in this group performed the PVC procedure directly on each other's arm veins without NIR or isometric exercise. Participants were asked about the degree of vein prominence after the tourniquet was applied, using inspection and palpation. The remaining stages were carried out in the same way as with all of the groups.

Interventions

The participant performing PVC carried out the procedure on the arm vein of another volunteer classmate with the help of vein imaging by NIR. All interventions were conducted under the observation of the researchers.

NIR light visualization

Before the procedure, the students on whom PVC was to be performed were given two stress balls, and they were told how to use them for 15 minutes. The participants were told to squeeze and relax the stress ball in the palm of their hands after counting from one to three, to continue doing this until the procedure began, and to concentrate on squeezing the ball.

isometric hand exercise

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • participants who did not use alcohol
  • participants who did not drug abuse
  • participants who completed the immunization /vaccination schedule.
  • participants who volunteered to participated in the study

You may not qualify if:

  • participants who were diagnosed with a chronic illness,
  • participants who have a disorder causing bleeding,
  • participants who have a psychiatric illness,
  • participants who had not received vaccinations for HBV, HCV, or HIV vaccine
  • participants who were pregnant
  • participants who did not volunteer to participate in the study were not included in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bursa Uludag University Health Sciences Faculty of the Nursing Department

Nilufer, Bursa, 16059, Turkey (Türkiye)

Location

Related Publications (5)

  • Clerkin R, Patton D, Moore Z, Nugent L, Avsar P, O'Connor T. What is the impact of video as a teaching method on achieving psychomotor skills in nursing? A systematic review and meta-analysis. Nurse Educ Today. 2022 Apr;111:105280. doi: 10.1016/j.nedt.2022.105280. Epub 2022 Jan 24.

  • Fukuroku K, Narita Y, Taneda Y, Kobayashi S, Gayle AA. Does infrared visualization improve selection of venipuncture sites for indwelling needle at the forearm in second-year nursing students? Nurse Educ Pract. 2016 May;18:1-9. doi: 10.1016/j.nepr.2016.02.005. Epub 2016 Feb 18.

  • Helm RE, Klausner JD, Klemperer JD, Flint LM, Huang E. Accepted but unacceptable: peripheral IV catheter failure. J Infus Nurs. 2015 May-Jun;38(3):189-203. doi: 10.1097/NAN.0000000000000100.

  • Filipovich SJ, Dilgard JW, Conrad SP, Moore CB, Hefley JB. Training Program for Ultrasound-Guided Intravenous Catheter Insertion. Mil Med. 2021 Aug 28;186(9-10):e879-e883. doi: 10.1093/milmed/usab176.

  • Yilmaz H, Yilmaz D, Cinar HG. The effect of three different techniques used to improve vein prominence on the first peripheral venous catheterization experience in nursing students: a randomized controlled study. BMC Med Educ. 2025 May 22;25(1):757. doi: 10.1186/s12909-025-07350-0.

MeSH Terms

Conditions

Behavior

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Because of the nature of the device and the procedure of venipuncture, blinding could not be performed
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: This is a prospective, randomized controlled experimental study.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, PhD, Msc

Study Record Dates

First Submitted

September 14, 2023

First Posted

September 28, 2023

Study Start

February 1, 2022

Primary Completion

July 31, 2022

Study Completion

July 31, 2022

Last Updated

September 28, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will not share

Locations