People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity

NCT06055868 | Recruiting

• 2 other identifiers: 23363R03DE032972
• Study Type: observational
• Target: 144
• Locations: 1 country
• Sites: 1

Brief Summary

This is an exploratory qualitative study among People Living With HIV (PLWH) of diverse racial/ethnic and sexual and gender minority (SGM) identities to explore individual, interpersonal, and structural oral health equity factors that serve as barriers or facilitators of accessing oral health care, knowledge and perceptions of human papillomavirus (HPV) vaccination and Oral squamous cell carcinoma (OSCC) /Oropharyngeal squamous cell carcinoma (OPSCC), and to collect recommendations on how to increase access to oral health care and engage PLWH in OSCC/OPSCC prevention.

Conditions

HIV Infections; Oral Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma

Keywords

Health Equity; Focus Group; Sexual and Gender Minority; People living with HIV; HPV, human papillomavirus

Outcome Measures

Primary Outcomes (1)

• Identification of potential oral health equity factors

  Participants will complete a baseline questionnaire which will aid in the formation of the focus group with other individuals of shared identity. The Focus Group Discussions (FGDs) will be transcribed, coded, and the focus group guide will be updated following the Grounded Theory qualitative research methodology. The "data" from the FGD are the audio recordings and the transcripts. The digital transcript of each focus group will be uploaded to the software MAXQDA to aid with coding and analysis in identifying individual, interpersonal, and structural factors, if any, that may impact accessing oral health care.

  Up to 3 days

Other Outcomes (2)

• Assess participant perceptions about OSCC/OPSCC and HPV vaccination

  During focus group, 1 day

• Assess participant knowledge about OSCC/OPSCC and HPV vaccination

  During focus group, 1 day

Study Arms (1)

Qualitative Focus Group

Participants will be asked to a series of questions to help place them in a focus group with other individuals of shared identity and will also complete a short quantitative survey either emailed to the participant or the outreach worker/study coordinator will administer the survey by phone. Participants will then participate in one 1.5-2 hour, facilitated, focus group discussions (FGD).

Other: Group Meeting (Focus Group); Other: Questionnaires

Interventions

Group Meeting (Focus Group) OTHER

Focus Group Discussions (FDGs) will be recorded, transcribed, and coded.

Qualitative Focus Group

Questionnaires OTHER

Given electronically or via phone by study team staff

Qualitative Focus Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

People living with HIV who identify with one or more racial/ethnic/ sexual or gender minority groups

You may qualify if:

• Participants must be 18-years old or older.
• Participants must be individuals living with HIV
• Ability to speak and understand English
• Identify as one or more racial/ethnic minority groups or sexual and gender minority groups
• All genders and members of all races and ethnic groups are eligible for this study.

You may not qualify if:

• Younger than 18-years old.
• Not living with HIV.
• Not able to speak and understand English.
• Not classified as one or more racial/ethnic minority groups or sexual and gender minority groups.

Sponsors & Collaborators

• University of California, San Francisco: lead
• National Institute of Dental and Craniofacial Research (NIDCR): collaborator

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94143, United States

RECRUITING

Related Publications (1)

• Hernandez AL, Lingas EO, Juarez W, Villa A, Palefsky J. Using an anti-racist research framework to design studies of oral human papillomavirus and oropharyngeal cancer in San Francisco: rationale and protocol for the Health Equity and Oral Health in People living with HIV (HEOHP) qualitative study. BMJ Open. 2024 Sep 24;14(9):e091474. doi: 10.1136/bmjopen-2024-091474.

  PMID: 39317508 DERIVED

MeSH Terms

Conditions

HIV Infections; Squamous Cell Carcinoma of Head and Neck; Coitus; Papillomavirus Infections

Interventions

Focus Groups; Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Carcinoma, Squamous Cell; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Head and Neck Neoplasms; Neoplasms by Site; Sexual Behavior; Behavior; DNA Virus Infections; Tumor Virus Infections; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Alexandra Hernandez Levenston, PhD, MPH

  University of California, San Francisco

  PRINCIPAL INVESTIGATOR

Central Study Contacts

William Juarez

CONTACT

(415) 437-7439; William.Juarez@ucsf.edu

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 20, 2023
• First Posted: September 28, 2023
• Study Start: February 13, 2025
• Primary Completion (Estimated): November 30, 2029
• Study Completion (Estimated): November 30, 2029
• Last Updated: May 28, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)