The Effect of Clinical Parameters on Muscle Oxygenation in Patients With COPD

NCT06041126 | Completed

• 1 other identifier: 2023-72
• Study Type: observational
• Target: 41
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine the peripheral muscle oxygenation of patients with Chronic Obstructive Pulmonary Disease at rest, during submaximal exercise and recovery, and to examine the effects of disease severity and respiratory functions on peripheral muscle oxygenations. In this study, the effect of disease severity and respiratory problems on peripheral muscle metabolism of patients with COPD will be explained.

Conditions

Chronic Obstructive Pulmonary Disease; Muscle Oxygenation; Disease Severity; Respiratory Function

Keywords

Chronic Obstructive Pulmonary Disease; Muscle Oxygenation; Disease Severity; Respiratory Function

Outcome Measures

Primary Outcomes (1)

• Muscle oxygenation

  The muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21

  one day

Secondary Outcomes (7)

• Modified Medical Research Council Dyspnea Scale

  one day

• COPD Assessment Test (CAT)

  one day

• Charlson Comorbidity Index

  one day

• Quadriceps muscle strength measurement

  one day

• Six-minute walking test

  one day

Study Arms (2)

Group one

Patients with COPD according to the combined COPD assessment Global Intervention (GOLD) guidelines, participants who are in groups A and B (mild-moderate) will be included in group 1.

Group two

COPD patients according to the combined COPD assessment, according to the "Global Intervention (GOLD) guidelines", participants who are in groups C and D (severe-very severe) will be included in group 2.

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Stable COPD Patients

You may qualify if:

• Being diagnosed with COPD (according to GOLD Staging: GOLD 1, GOLD 2, GOLD 3, GOLD 4)
• Being between the ages of 40-80
• Body Mass Index \<35
• Not having an acute exacerbation in the last 3 months

You may not qualify if:

• Patients who do not want to participate in the study
• Arthritis causing weakness in the lower extremity, neurological disease, deep vein thrombosis, peripheral arterial disease, muscle weakness, fracture etc. patients with the condition
• Common diseases such as malignancy, pulmonary embolism, vasculitis, collagen tissue diseases, interstitial fibrosis, severe pneumonia patients with parenchymal destruction
• Patients with severe dyspnea and hemodynamic instability who cannot perform the 6 Minute Walk Test

Sponsors & Collaborators

• Bandırma Onyedi Eylül University: lead

Study Sites (1)

Bandırma Onyedi Eylül University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Balıkesir, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Aspiration

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 27, 2023
• First Posted: September 18, 2023
• Study Start: April 24, 2023
• Primary Completion: June 23, 2024
• Study Completion: March 1, 2025
• Last Updated: March 13, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)