Muscle Oxygenation in Chronic Obstructive Pulmonary Disease

NCT05808621 | Completed

• 1 other identifier: 2023-19
• Study Type: observational
• Target: 41
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of our study is to examine the Peripheral Muscle Oxygenations at rest and in motion on the 2nd day of hospitalized patients and before discharge in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease and to compare the results in the hospital periods by repeating the tests in the stable periods of the patients 1 month after discharge.

Conditions

Chronic Obstructive Pulmonary Disease; Chronic Obstructive Pulmonary Disease Exacerbation; Muscle Oxygenation

Keywords

Chronic Obstructive Pulmonary Disease; Muscle Oxygenation; Chronic Obstructive Pulmonary Disease Exacerbation

Outcome Measures

Primary Outcomes (1)

• Muscle oxygenation

  The muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21 mm) device that measures regional blood flow and oxygenation by placing it on the skin non-invasively with near infrared spectroscopy (NIRS). The device, which has data collection and telemetric features, also allows O 2 measurement in non-laboratory environments and field-based research.

  4 weeks

Secondary Outcomes (4)

• 1 minute sit and stand test

  4 weeks

• Modified Medical Research Council Dyspnea Scale:

  4 weeks

• COPD Assessment Test (CAT)

  4 weeks

• Charlson Comorbidity Index

  4 weeks

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

COPD hospitalized with Severe Acute Exacerbation

You may qualify if:

• Being a COPD patient hospitalized with Severe Acute Exacerbation
• be between 40-80 years old
• Having a Body Mass Index below 35

You may not qualify if:

• Patients who do not want to participate in the study
• Patients requiring intensive care follow-up during their hospitalization Arthritis, neurological disease, deep vein thrombosis, peripheral arterial disease, muscle weakness, broken etc. patients with the condition
• Extensive parenchyma such as malignancy, pulmonary embolism, vasculitis, collagen tissue diseases, interstitial fibrosis, severe pneumonia patients with damage
• Patients with severe dyspnea and hemodynamic instability who cannot perform the sit-up test

Sponsors & Collaborators

• Bandırma Onyedi Eylül University: lead

Study Sites (1)

Bandırma Onyedi Eylül University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Balıkesir, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: March 13, 2023
• First Posted: April 11, 2023
• Study Start: March 8, 2023
• Primary Completion: June 23, 2024
• Study Completion: March 10, 2025
• Last Updated: March 13, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)