NCT06040606

Brief Summary

Postoperative complications and mortality in patients with COVID-19 Omicron infection who have undergone specialized thoracic surgery are scarce. Subsequently, the patient cohort was divided into two groups for comparative analysis: Group 1 (G1), which comprised patients who acquired nosocomial omicron infection after surgery, and Group 2 (G2), which comprised patients who remained uninfected with omicron during their hospitalization period. Propensity score matching (PSM) analysis was conducted using the PSMATCH function in SPSS 27 to assess the incidence of perioperative complications and mortality rates between both groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
119

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2023

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 31, 2023

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 15, 2023

Completed
Last Updated

September 15, 2023

Status Verified

September 1, 2023

Enrollment Period

2 months

First QC Date

August 31, 2023

Last Update Submit

September 8, 2023

Conditions

Keywords

Thoracic surgery; Postoperative complications; Mortality

Outcome Measures

Primary Outcomes (2)

  • Postoperative Complications

    Postoperative Complications

    up to 1 months

  • Postoperative Mortality

    Postoperative Mortality

    up to 1 months

Study Arms (2)

Group 1 (G1)

patients who acquired nosocomial omicron infection after surgery

Procedure: In-Hospital COVID-19 Omicron Infection after surgery

Group 2 (G2)

patients who remained uninfected with omicron during their hospitalization period

Interventions

Thoracic Surgery Patients with In-Hospital COVID-19 Omicron Infection after surgery

Group 1 (G1)

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Data of patients who underwent thoracic surgery at the Tangdu Hospital of Air Force Medical University and the Second Affiliated Hospital of Lanzhou University between December 1, 2022, and January 15, 2023, were collected.

You may qualify if:

  • Data of patients who underwent thoracic surgery at the Tangdu Hospital of Air Force Medical University and the Second Affiliated Hospital of Lanzhou University between December 1, 2022, and January 15, 2023, were collected.

You may not qualify if:

  • Non-surgery patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Second Affiliated Hospital of Air Force Medical University University of PLA

Xi'an, Shannxi, China

Location

MeSH Terms

Conditions

Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Linna Liu

    Tang-Du Hospital

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Deputy director

Study Record Dates

First Submitted

August 31, 2023

First Posted

September 15, 2023

Study Start

February 1, 2023

Primary Completion

March 31, 2023

Study Completion

March 31, 2023

Last Updated

September 15, 2023

Record last verified: 2023-09

Locations