Effectiveness of a Cancer Exercise Program

NCT06039488 | Enrolling By Invitation

• 1 other identifier: Pro00109975
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (\>18 years old) with cancer.

Conditions

Cancer

Keywords

Exercise

Outcome Measures

Primary Outcomes (3)

• Bellarmine Norton Assessment Tool (2-minute Step Test)

  2-minute Step Test: Number of times an individuals' knee reaches a predetermined heigh during a 2-minute period of marching

  0 and 8-weeks

• Bellarmine Norton Assessment Tool (Timed Arm Curl)

  Timed Arm Curl: Number of repetitions an arm curl individuals can complete in 30 seconds)

  0 and 8-weeks

• Bellarmine Norton Assessment Tool (30 second Chair Stand)

  Chair Stand: Number of times participants can stand from a sitting position and return to sitting in 30 seconds

  0 and 8-weeks

Secondary Outcomes (1)

• Fatigue

  0 and 8-weeks

Study Arms (1)

Exercise

EXPERIMENTAL

2 days/week of resistance and cardiovascular exercise for 8-weeks

Behavioral: Exercise

Interventions

Exercise BEHAVIORAL

A combination of resistance exercise and cardiovascular exercise (performed 2 days per week for 8-weeks) is tailored to each individual in accordance with their medical/cancer-related history, baseline assessments of physical function, and overall goals. Resistance exercise includes 6-8 exercises targeting major muscle groups. The first week of the program is used to familiarize participants to the exercises of the program, provide coaching on safe and appropriate technique, and identifying initial load for 2 sets of 12 repetitions (equivalent to \~65% 1 repetition maximum), with a goal of working towards 4 sets of 8 reps. Additionally, participants are asked to perform 20-30 minutes of moderate-to-vigorous aerobic activity (approximately 60-85% age-predicted heart rate maximum) via walking, jogging, or cycling each session.

Exercise

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults \> 18 diagnosed with cancer

You may not qualify if:

• unwilling to come to the on-site clinic for exercise sessions
• any neuromuscular, cardiovascular, or psychological condition precluding safe exercise
• unable to read/understand English.

Sponsors & Collaborators

• University of South Carolina: lead

Study Sites (1)

University of South Carolina

Columbia, South Carolina, 29205, United States

Location

Related Publications (1)

• Fairman CM, Harrington SE, Schumpp AR, Brooks AM, Jones MJ, Kim J, Kennedy MA. Planning and evaluating an integrated clinical exercise oncology service: an exploratory mixed-methods study. BMC Health Serv Res. 2024 Oct 31;24(1):1318. doi: 10.1186/s12913-024-11797-0.

  PMID: 39478564 DERIVED

MeSH Terms

Conditions

Neoplasms; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 5, 2023
• First Posted: September 15, 2023
• Study Start: August 15, 2021
• Primary Completion: January 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: September 15, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)