Uterine Peristalsis in IVF
Effect of Uterine Peristalsis at the Time of Embryo Transfer on the Outcomes of IVF Cycles: a Prospective Cohort Study
Effect of Uterine Peristalsis at the Time of Embryo Transfer on the Outcomes of IVF Cycles: a Prospective Cohort Study
Sponsor study identifier
observational
117
0 countries
N/A
Study Start
October 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
October 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
An observational prospective cohort study to evaluate the effect of uterine peristalsis at the time of embryo transfer on IVF clinical outcomes performed in Women's Health hospital, Assiut University, Egypt. Women performing fresh or frozen embryo transfer who do not have any uterine abnormalities will be included in the study
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 13, 2023
Actual (reported)September 14, 2023
Actual (reported)October 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
October 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Clinical pregnancy
The presence of intrauterine gestational sac and fetal pole with positive cardiac pulsation by transvaginal ultrasound
2 weeks after a positive pregnancy test
Biochemical pregnancy
2 weeks after embryo transfer
Miscarriage
From 6 weeks of gestation until 28 weeks of gestation
Ectopic pregnancy
the site of the gestational sac will be assessed 2 weeks after embryo transfer
Ongoing pregnancy
After 12 weeks of gestation until delivery
Live birth
From 28 weeks of gestation until delivery
Transabdominal us followed by Transvaginal ultrasonography scans (Sono Ace R5 ) of uterine peristalsis will performed on the day of embryo transfer while the patient lying relaxed in lithotomy position. The probe will be introduced into the vagina as gently as possible to avoid stimulating the cervix. After scanning the mid-sagittal plane of the uterus, the probe will be fixed as steady as possible while a 3 min video of uterine peristalsis will be recorded simultaneously. The records will be analyzed at 4X regular speed using a Video player application by two independent experienced observers. The uterine peristaltic wave frequency will be the mean of the results from each observer.
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Women undergoing IVF
Abdallah KS, Zahran KM, Othman MA, Nasr A. Effect of uterine peristalsis at the time of embryo transfer on the outcomes of IVF cycles: a prospective cohort study. Reprod Biol Endocrinol. 2026 Jul 9;24(1):72. doi: 10.1186/s12958-026-01587-0.
Mahmoud Abdelaziz, M.Sc
Assiut University
First Submitted
August 13, 2023
First Posted
September 14, 2023
Study Start
October 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
October 2025
The Role of Erzhi Tiangui Formula in Expected POR Women Undergoing IVF-ET
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
September 21, 2023
Record last verified: 2023-09
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Source: ClinicalTrials.gov.
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