Comparisons of Two Airway Clearance Techniques
Comparison of Two Airway Clearance Techniques by Electrical Impedance Tomography- a Parallel Study
1 other identifier
interventional
30
1 country
2
Brief Summary
The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are:
- effect of the therapies on volume changes
- outcome on sputum clearance Participants will receive airway clearance techniques of
- chest physiotherapy
- high frequency chest wall oscillation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2023
Shorter than P25 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 16, 2023
CompletedFirst Submitted
Initial submission to the registry
September 5, 2023
CompletedFirst Posted
Study publicly available on registry
September 13, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 12, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2023
CompletedSeptember 19, 2024
September 1, 2024
9 months
September 5, 2023
September 15, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
end-expiratory lung impedance
Changes of global of impedance of lungs measure by the electrical impedance tomography
Measurement before intervention, 30 after, 1 hour and 2 hours after intervention
Secondary Outcomes (1)
Weight of secretions
Sputum is collected before intervention, 30 after, 1 hour and 2 hours after intervention
Study Arms (2)
Chest physiotherapy
EXPERIMENTALPatients receive airway clearance by chest physiotherapy for 30 minutes twice a day.
High frequency chest wall oscillation
EXPERIMENTALParticipants received high frequency chest wall oscillation therapy twice a dy
Interventions
Patients receive airway clearance by high frequency chest wall oscillation for 30 minutes twice a day.
Participants received chest physiotherapy twice a day
Eligibility Criteria
You may qualify if:
- Diagnosed with chronic pulmonary disease
- Diagnosed with ventilator associated pneumonia
- Receive airway clearance therapy
You may not qualify if:
- Head injury, spinal injury
- Instable hemodynamics
- Intercranial pressure \> 20 cmH2O
- Active hemoptysis
- Empyema
- Eye surgery
- Abdominal distension
- Chest tube insertion
- Active tuberculosis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hui-Ling Linlead
Study Sites (2)
Linkou Chang Gung Memorial Hospital
Taoyuan District, 33305, Taiwan
Chang Gung Memorial Hospital
Taoyuan District, 61363, Taiwan
Related Publications (1)
Rowley DD, Malinowski TP, Di Peppe JL, Sharkey RM, Gochenour DU, Enfield KB. A Randomized Controlled Trial Comparing Two Lung Expansion Therapies After Upper Abdominal Surgery. Respir Care. 2019 Oct;64(10):1181-1192. doi: 10.4187/respcare.06812. Epub 2019 May 21.
PMID: 31113857RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hui-Ling Lin, PhD
Chang Gung University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Masking Details
- The group will be coded and masked to the investigator and the outcome accessor.
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
September 5, 2023
First Posted
September 13, 2023
Study Start
March 16, 2023
Primary Completion
December 12, 2023
Study Completion
December 30, 2023
Last Updated
September 19, 2024
Record last verified: 2024-09