NCT06031038

Brief Summary

M-TECCU is a study: multicenter, randomized and open. It consists of two parallel groups to compare the efficacy of the TECCU web-based telemonitoring system to achieve and maintain activity remission in patients with moderate-high complexity inflammatory bowel disease compared to usual clinical practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
290

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

30 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 15, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 13, 2021

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

July 24, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

September 11, 2023

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 5, 2025

Completed
Last Updated

February 6, 2026

Status Verified

February 1, 2026

Enrollment Period

1.1 years

First QC Date

July 24, 2023

Last Update Submit

February 4, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • clinical remission

    To compare the time in remission of patients with complex IBD (require immunosuppressants and/or biologics to control their luminal inflammatory activity) controlled with the TECCU intervention (G\_TECCU) with respect to usual clinical practice (G\_Control) after 52 weeks of follow-up.

    52 weeks

Secondary Outcomes (1)

  • cost-effectiveness

    52 weeks

Study Arms (2)

Control group

NO INTERVENTION

Patients receive conventional care in the outpatient clinics of the participating specialized IBD units in Spain. This is complemented with telephone controls for those aspects that can be controlled by this means according to standard clinical practice. Likewise, an individual assessment will be made if, after the situation generated by SARS-COV2, any participating center should have to modify face-to-face consultations for telephone consultations, following the usual clinical practice at all times.

Web telemonitoring group (G_TECCU)

ACTIVE COMPARATOR

Monitoring and control will be done remotely through the TECCU comprehensive management platform, configured to respond to the specific needs of IBD patients. Patients will connect to the internet from a computer or an APP application on a tablet or mobile terminal, Android or iOS. They will have to complete questionnaires related to the variables under study at each control according to a pre-established follow-up plan. During the follow-up, the number of controls may be increased (intensive monitoring) according to the evolution of the patient, who in turn will be able to perform controls on demand. The healthcare personnel of each IBD unit will receive the information of each patient filtered through an intelligent alert generation system from which an integrated intervention protocol will be followed to adjust the treatment and follow-up plan in each case.

Other: TECCU Software

Interventions

patient monitoring by software application

Web telemonitoring group (G_TECCU)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients ≥18a
  • IBD (CD or UC) diagnosed according to ECCO criteria
  • Start treatment with immunosuppressants and/or biological therapies due to luminal activity
  • signed informed consent

You may not qualify if:

  • Pregnant women
  • Presence of active perianal disease, ileoanal reservoir, or definitive stoma
  • Patients with mental illness or other poorly controlled illness
  • Patients with active cancer diagnosis
  • Terminal patients and/or palliative care (SECPAL)
  • Family members of the research team
  • Patients without a telephone line to connect with a mobile, tablet and/or computer / Inability to drive
  • Cognitive or linguistic difficulties
  • Patients included in another experimental study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (30)

Hospital Universitario y Politécnico la Fe

Valencia, Valencia, 46026, Spain

Location

Hospital Universitario de Alicante

Alicante, Spain

Location

Hospital Germans Trias i Pujol

Badalona, Spain

Location

Hospital Universitario de Burgos

Burgos, Spain

Location

Hospital Universitario de Cabueñes

Cabueñes, Spain

Location

Hospital Universitario Reina Sofía

Córdoba, Spain

Location

Hospital de Cruces

Cruces, Spain

Location

Hospital General Universitario de Elche

Elche, Spain

Location

Hospital Universitario de Fuenlabrada

Fuenlabrada, Spain

Location

Hospital Trueta de Girona

Girona, Spain

Location

Hospital Universitario San Cecilio

Granada, Spain

Location

Hospital de Huelva

Huelva, Spain

Location

Hospital Gregorio Marañón

Madrid, Spain

Location

Hospital La Paz

Madrid, Spain

Location

Hospital La Princesa

Madrid, Spain

Location

Hospital Puerta del Hierro

Madrid, Spain

Location

Hospital Ramon y Cajal

Madrid, Spain

Location

Hospital de Manresa

Manresa, Spain

Location

Hospital Morales Meseguer

Murcia, Spain

Location

Hospital Parc Taulí de Sabadell

Sabadell, Spain

Location

Hospital Infanta Sofía

San Sebastián de los Reyes, Spain

Location

Hospital Nuestra Señora de la Candelaria

Santa Cruz de Tenerife, Spain

Location

Hospital Marqués de Valdecilla

Santander, Spain

Location

Hospital Universitario de Santiago

Santiago de Compostela, Spain

Location

Consorci Sanitari de Terrassa

Terrassa, Spain

Location

Hospital Universitario Mutua Terrassa

Terrassa, Spain

Location

Hospital Clínico Universitario Valencia

Valencia, Spain

Location

Hospital de Vigo

Vigo, Spain

Location

Hospital Clínico Universitario Lozano Blesa

Zaragoza, Spain

Location

Hospital Universitario Miquel Servet

Zaragoza, Spain

Location

Related Publications (4)

  • Del Hoyo J, Nos P, Faubel R, Munoz D, Dominguez D, Bastida G, Valdivieso B, Correcher M, Aguas M. A Web-Based Telemanagement System for Improving Disease Activity and Quality of Life in Patients With Complex Inflammatory Bowel Disease: Pilot Randomized Controlled Trial. J Med Internet Res. 2018 Nov 27;20(11):e11602. doi: 10.2196/11602.

    PMID: 30482739BACKGROUND
  • Aguas M, Del Hoyo J, Faubel R, Munoz D, Dominguez D, Bastida G, Navarro B, Barrios A, Valdivieso B, Correcher M, Nos P. A Web-Based Telemanagement System for Patients With Complex Inflammatory Bowel Disease: Protocol for a Randomized Controlled Clinical Trial. JMIR Res Protoc. 2018 Dec 21;7(12):e190. doi: 10.2196/resprot.9639.

    PMID: 30578197BACKGROUND
  • Del Hoyo J, Aguas M. Cost-effectiveness of Telemedicine-directed Specialized vs Standard Care for Patients With Inflammatory Bowel Diseases in a Randomized Trial. Clin Gastroenterol Hepatol. 2021 Jan;19(1):206-207. doi: 10.1016/j.cgh.2020.06.016. No abstract available.

    PMID: 33339564BACKGROUND
  • Aguas M, Del Hoyo J, Vicente R, Barreiro-de Acosta M, Melcarne L, Hernandez-Camba A, Madero L, Arroyo MT, Sicilia B, Chaparro M, Martin-Arranz MD, Pajares R, Mesonero F, Manosa M, Martinez P, Chacon S, Tosca J, Marin S, Sanroman L, Calvo M, Monfort D, Saiz E, Zabana Y, Guerra I, Varela P, Baydal V, Faubel R, Corsino P, Porto-Silva S, Brunet E, Gonzalez M, Gutierrez A, Nos P. Telemonitoring of Active Inflammatory Bowel Disease Using the App TECCU: Short-Term Results of a Multicenter Trial of GETECCU. J Med Internet Res. 2024 Nov 18;26:e60966. doi: 10.2196/60966.

MeSH Terms

Conditions

Inflammatory Bowel DiseasesCrohn DiseaseColitis, Ulcerative

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesColitisColonic Diseases

Study Officials

  • Mariam Aguas

    Spanish Working Group on Crohn's disease and ulcerative colitis (GETECCU)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: To compare the time in remission of patients with complex IBD (require immunosuppressants and/or biologics to control their luminal inflammatory activity) controlled with the TECCU intervention (G\_TECCU) with respect to usual clinical practice (G\_Control) after 52 weeks of follow-up.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 24, 2023

First Posted

September 11, 2023

Study Start

September 15, 2020

Primary Completion

October 13, 2021

Study Completion

June 5, 2025

Last Updated

February 6, 2026

Record last verified: 2026-02

Locations