Adherence to Lung Cancer Screening by Low-dose Thoracic CT in Haut-Rhin Department, France.

NCT06020443 | Active Not Recruiting

• 2 other identifiers: GHRMSA 13032023-A00803-42
• Study Type: interventional
• Target: 126
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective of the study is to measure adherence to a lung cancer screening program using low-dose thoracic CT.

Conditions

High-Risk Cancer; Lung Cancer

Keywords

screening; low dose chest computed tomography; lung cancer

Outcome Measures

Primary Outcomes (1)

• Rate of included patients having undergone the first screening scan

  T0

Secondary Outcomes (7)

• Rate of patients who refused to participate in the screening program

  1 year

• Rate of included patients having completed CT scans at each stage of follow-up

  3 years

• Number of patients newly committed to smoking cessation during the screening period

  3 years

• Tobacco consumption

  3 years

• Radiation doses received at each CT scan

  3 years

Study Arms (1)

Patients with a high risk of lung cancer

OTHER

Procedure: Low Dose chest CT Scan for Lung Cancer Screening

Interventions

Low Dose chest CT Scan for Lung Cancer Screening PROCEDURE

Low dose CT scans will be performed for three years

Patients with a high risk of lung cancer

Eligibility Criteria

• Age: 50 Years - 74 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 50 to 74 years
• Smoking OR having smoked (withdrawal of \<15 years): ≥15 cigarettes/day for ≥25 years OR ≥10 cigarettes/day for ≥30 years
• Affiliated or beneficiary of a social security scheme
• Written informed consent

You may not qualify if:

• Inability to walk up two flights of stairs without stopping
• BMI \> 35 kg/m²
• Recent chest CT scan \< 1 year
• Personal history of lung cancer \< 5 years or under treatment
• Personal history of cancer being monitored by chest CT scan
• Contraindication to lung cancer treatment or diagnostic investigations
• Current or recent respiratory symptoms immediately suggestive of lung cancer
• Pregnant or breast-feeding woman
• Person under court protection, guardianship or curatorship
• Person deprived of liberty by judicial or administrative decision.

Sponsors & Collaborators

• Groupe Hospitalier de la Region de Mulhouse et Sud Alsace: lead

Study Sites (1)

Cabinet de médecine générale

Colmar, Haut-Rhin, 68000, France

Location

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Patrick Strentz, MD

  General Practioner, Colmar, France

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Low Dose chest CT Scan for Lung Cancer Screening

Study Record Dates

• First Submitted: August 28, 2023
• First Posted: August 31, 2023
• Study Start: November 6, 2023
• Primary Completion: November 5, 2024
• Study Completion (Estimated): November 1, 2026
• Last Updated: May 16, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)