Joint Thoracic Oncology Research Unit of LYon: Lung cancerS DatabaSE (ULYSSE)

NCT05267041 | Recruiting

• 1 other identifier: 69HCL21_1175
• Study Type: interventional
• Target: 4,000
• Locations: 1 country
• Sites: 1

Brief Summary

Prospective longitudinal cohort associated to blood collection, pathological samples collection, and radiological and pathological imaging collection.

Conditions

Lung Cancer

Keywords

Data collection; lung cancer

Outcome Measures

Primary Outcomes (1)

• Number of participants registered in the lung cancer database

  cohort open to recruitment during 10 years with 10 years of patients follow-up

  20 years

Study Arms (1)

Cohort of Adults with lung cancer

EXPERIMENTAL

Patients newly diagnosed with lung cancer.

Biological: Blood sample; Other: Questionnaire

Interventions

Blood sample BIOLOGICAL

One optional veinous blood sampling (24 ML) between the first diagnostic annoucement and before the first treatment for lung cancer

Cohort of Adults with lung cancer

Questionnaire OTHER

to collect data not reported in the patient's medical file, such as passive smoking, family history of cancer, and attempts to quit smoking.

Cohort of Adults with lung cancer

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient treated for a thoracic cancer in the Lyon University Hospital: non-small cell lung cancer, small cell lung cancer, mesothelioma…
• Diagnosis can be done:
• By cytology or pathologic assessment
• Or by multidisciplinary team meeting decision:
• Irradiation without morpho-metabolic sampling
• Treatment without sampling based on non-invasive molecular data

You may not qualify if:

• \- Refusal to participate
• For optional blood sampling :
• \< 30 kg for blood collection
• No blood sampling schedule for care

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Centre Hospitalier Lyon Sud

Pierre-Bénite, 69495, France

RECRUITING

MeSH Terms

Conditions

Lung Neoplasms

Interventions

Blood Specimen Collection; Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques; Data Collection; Epidemiologic Methods; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: One questionnaire between diagnostic annoucement and first line treatement One 6 months later One before second line treatment One 6 months later after second line treatment Optionnal Veinous Blood Sample (28 mL) between the diagnostic annoucement and the first line of treatment

Study Record Dates

• First Submitted: February 14, 2022
• First Posted: March 4, 2022
• Study Start: May 5, 2022
• Primary Completion (Estimated): May 5, 2032
• Study Completion (Estimated): May 5, 2042
• Last Updated: November 21, 2025

Record last verified: 2025-11

Locations

FR (1)