NCT06016166

Brief Summary

This randomized clinical trial (RCT) was aimed to determine the effects of eye masking on sleep quality and tear layer function in patients with dry eye disease. In this regard, a total of 34 patients with dry eye disease aged between 20 to 35 years old will be participated. They will be randomly divided into case and control (n=17) groups. Patients in the case group will be instructed to wear the eye mask as long as two weeks and the controls will be recommended to not wear it at the same time. Afterwards, the eye mask application will be cross- over for the next 2 hours between the two groups. Tear layer will be investigated in baseline and repeated in both follow- ups of weeks 2 and 4, either quantitatively and qualitatively, by using Schirmer and TBUT tests. Furthermore, the sleep quality will be checked by the PSQI test.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2023

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 15, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

August 29, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

October 1, 2023

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

August 29, 2023

Status Verified

August 1, 2023

Enrollment Period

11 months

First QC Date

August 15, 2023

Last Update Submit

August 24, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • The effect of using eye mask on tear layer functions between baseline and follow- ups of weeks 2 and 4 in patients with dry eye

    Tear film function is measured quantitatively and qualitatively by the Schirmer (based on millimeters) and TBUT ( based on seconds) test

    between baseline and follow- ups of weeks 2 and 4

  • The effect of using eye mask on sleep quality between baseline and follow- ups of weeks 2 and 4 in patients with dry eye

    Sleep quality is measured by PSQI test based on the obtained score

    between baseline and follow- ups of weeks 2 and 4

Study Arms (2)

Eye mask users

EXPERIMENTAL

The eyes of the patients will be defined as the intervention

Device: Eye mask

Non eye mask users

NO INTERVENTION

The eyes of the patients will be defined as the controls

Interventions

Eye maskDEVICE

The 3D eye mask with the ability to adjust for different faces and eliminate light

Eye mask users

Eligibility Criteria

Age20 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with dry eye disease according to the OSDI test

You may not qualify if:

  • Patients with eye disease except dry eye
  • Patients using systemic and ophthalmic drugs
  • Patients using sleeping and sedative pills

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hamideh Sabbaghi

Tehran, Iran

Location

MeSH Terms

Conditions

Dry Eye Syndromes

Condition Hierarchy (Ancestors)

Lacrimal Apparatus DiseasesEye Diseases

Central Study Contacts

Hamideh Sabbaghi, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 15, 2023

First Posted

August 29, 2023

Study Start

October 1, 2023

Primary Completion

September 1, 2024

Study Completion

December 1, 2024

Last Updated

August 29, 2023

Record last verified: 2023-08

Locations