Dry Eye Disease
214
14
18
147
Key Insights
Highlights
Success Rate
97% trial completion (above average)
Published Results
52 trials with published results (24%)
Research Maturity
147 completed trials (69% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
2.3%
5 terminated out of 214 trials
96.7%
+10.2% vs benchmark
29%
61 trials in Phase 3/4
35%
52 of 147 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 147 completed trials
Clinical Trials (214)
A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants Following Anti-inflammatory Treatment
Evaluation of Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray
Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease
Evaluation of Tears Naturale® Free and Tears Naturale® II Lubricant Eye Drops
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease
Phase 2b Controlled Study
A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes
Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease
An Evaluation of the Safety and Tolerability of Ocular Lubricants
A Study to Evaluate the Safety and Effectiveness of Perfluorohexyloctane Eye Drops on Treatment of Dry Eye Disease (DED) Related to Meibomian Gland Dysfunction (MGD)
Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease
Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).
A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.
IVW-1001 Phase 1/2 in Subjects With Dry Eye Disease
A Study Designed to Evaluate Tear Production
A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.
Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease
Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease