Dry Eye Disease
215
12
16
151
Key Insights
Highlights
Success Rate
97% trial completion (above average)
Published Results
53 trials with published results (25%)
Research Maturity
151 completed trials (70% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
2.3%
5 terminated out of 215 trials
96.8%
+10.2% vs benchmark
28%
61 trials in Phase 3/4
35%
53 of 151 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 151 completed trials
Clinical Trials (215)
An Evaluation of the Safety and Tolerability of Ocular Lubricants
A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants Following Anti-inflammatory Treatment
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease
Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).
Evaluation of Tears Naturale® Free and Tears Naturale® II Lubricant Eye Drops
Phase III Study of Topical Fibrinogen-Depleted Human Platelet Lysate Compared to Placebo for Moderate to Severe Dry Eye
Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease
Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease
Human Umbilical Cord Mesenchymal Stem Cell-derived Small Extracellular Vesicles for the Treatment of Dry Eye Disease
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
Evaluation of Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray
Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease
Phase 2b Controlled Study
A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes
Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)
A Study to Evaluate the Safety and Effectiveness of Perfluorohexyloctane Eye Drops on Treatment of Dry Eye Disease (DED) Related to Meibomian Gland Dysfunction (MGD)
Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease
A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.