Carpal Tunnel Syndrome Evaluation With Ultrasound in Rheumatoid Arthritis Patients

NCT06012630 | Completed

• 1 other identifier: 22/04/2022; 2011-KAEK-50;126
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

In rheumatoid arthritis (RA) patients, the diagnosis of Carpal tunnel syndrome (CTS) was made based on clinical findings and physical examinations. Then, the cross-sectional areas of the participants' median nerves from different levels were measured. Meidolateral and anteroposterior diameter were measured at the level of the carpal tunnel inlet. Flattening ratio was calculated. wrist to forearm ratio and wrist to forearm difference were calculated. The obtained data were compared between RA with CTS, RA without CTS and healthy control.

Conditions

Median Nerve Entrapment

Keywords

Rheumatoid arthritis; Ultrasound; Carpal Tunnel Syndrome

Outcome Measures

Primary Outcomes (1)

• Comparison of US findings among participants

  Comparison of US findings among participants

  6 months

Secondary Outcomes (1)

• Relationship between US findings and disease activity in the patient group

  6 months

Study Arms (3)

group 1: RA without CTS

Rheumatoid arthritis patients without a diagnosis of CTS based on clinical findings and physical examination

Diagnostic Test: Ultarsound

group 2: RA with CTS

Rheumatoid arthritis patients with a diagnosis of CTS based on clinical findings and physical examination

Diagnostic Test: Ultarsound

group:3 Healthy Control

Healthy Control without rheumatologic disease and Carpal tunnel syndrome

Diagnostic Test: Ultarsound

Interventions

Ultarsound DIAGNOSTIC_TEST

Median nerve evaluation of participants with ultrasound

group 1: RA without CTS; group 2: RA with CTS; group:3 Healthy Control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria healthy controls (HC) with no history of rheumatic diseases and CTS.

You may qualify if:

• RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria
• healthy controls (HC) with no history of rheumatic diseases and CTS.
• Individuals aged 18-65 years.

You may not qualify if:

• thoese with hypothyroidism,
• gout,
• diabetes mellitus,
• history of CTS surgery,
• upper extremity plexopathy,
• polinöropathy,
• uncontrollable fibromyalgia,
• steroid injection for CTS
• For the HC group, those with phalen or tinnel detected in at least one wrist and those with bifid median nerve detected during US evaluation were not included in the study.

Sponsors & Collaborators

• Burak Tayyip Dede: lead

Study Sites (1)

Istanbul Training and Resarch Hospital

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Median Neuropathy; Arthritis, Rheumatoid; Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 8 Months
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Physical Medicine and Rehabilitation

Study Record Dates

• First Submitted: August 17, 2023
• First Posted: August 25, 2023
• Study Start: January 15, 2023
• Primary Completion: July 1, 2023
• Study Completion: August 15, 2023
• Last Updated: August 25, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will share

Locations

TU (1)