A Study of Physical Activity in Cancer Survivors

NCT05988892 | Completed

• 2 other identifiers: 23-001462NCI-2023-05387
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 4

Brief Summary

The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors \> 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors \>60 years of age and/or those of any age residing at a rural address.

Conditions

Cancer; Hematopoietic and Lymphatic System Neoplasm; Malignant Solid Neoplasm

Keywords

Rural; Physical Activity

Outcome Measures

Primary Outcomes (4)

• Change in physical functioning using Short Physical Performance Battery

  Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention.

  Baseline; 12 weeks

• Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS)

  QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention.

  Baseline; 12 weeks

• Change in satisfaction using a 5-point Likert scale

  Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program.

  Baseline; 12 weeks

• Rate of adherence to program based on participation in virtual exercise sessions

  Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention.

  Baseline; 12 weeks

Study Arms (1)

Community Oncology patients entering cancer survivorship

EXPERIMENTAL

Patients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive bi-weekly phone calls/emails over 12 weeks. Patents also wear a Fitbit on study.

Behavioral: Physical Activity

Interventions

Physical Activity BEHAVIORAL

Use Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors \>60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors \>60 years of age and/or those of any age residing at a rural address.

Community Oncology patients entering cancer survivorship

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI), Southwest Wisconsin (SWWI), Southeast Minnesota (SEMN), or Southwest Minnesota (SWMN)
• Any stage cancer
• Age \>= 18 years residing at a rural address (as defined by Rural America, census.gov Urban Areas 2020 metric)
• Age ≥ 18 years residing at a rural address (as defined by Rural America, census.gov)
• Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible.
• Ownership of a computer/tablet/smartphone with internet access.
• Willingness to create a google account and maintain the account for use of the Fitbit
• Willingness and ability to attend study visits.
• Must be able to complete semi-tandem (10 seconds), side-by-side tandem \[10 seconds and short physical performance batters(SPPB)\] Score of 6 or greater to qualify for virtual exercise.
• Must be ambulatory without the use of assisted device(s).

You may not qualify if:

• Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment
• Are already performing \>150 minutes/week of moderate activity or 75 min/week of vigorous physical activity
• Cancer-free for greater than 5 years
• Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.
• Squamous cell or basal cell skin cancers (melanoma still eligible)
• Stage 0/in situ vulvar/cervical cancers

Sponsors & Collaborators

• Mayo Clinic: lead

Study Sites (4)

Mayo Clinic Health System in Albert Lea

Albert Lea, Minnesota, 56007, United States

Location

Mayo Clinic Health System-Mankato

Mankato, Minnesota, 56001, United States

Location

Mayo Clinic Health System-Eau Claire Clinic

Eau Claire, Wisconsin, 54701, United States

Location

Mayo Clinic Health System-Franciscan Healthcare

La Crosse, Wisconsin, 54601, United States

Location

Related Links

• Mayo Clinic Clinical Trials

MeSH Terms

Conditions

Neoplasms; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Kaye T. Sturz, APRN, CNP

  Mayo Clinic Health System in Eau Claire

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 26, 2023
• First Posted: August 14, 2023
• Study Start: June 29, 2023
• Primary Completion: April 23, 2025
• Study Completion: April 23, 2025
• Last Updated: March 23, 2026

Record last verified: 2025-10

Locations

US (4)