NCT05983055

Completed

Steroid Injection for Sickle Cell Arthropathy Pain Therapy

Salem Anaesthesia Pain Clinic Source

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Other study identifiers

Sponsor study identifier

SalemAn2018 SCD arthro injectn

Study Type

observational

Actual enrollment (reported)

50

Locations

1 country

Sites

1

Timeline

Study Start

January 30, 2018

Actual (reported)

Primary Completion

March 31, 2024

Actual (reported)

Study Completion

March 31, 2024

Actual (reported)

Brief Summary

Sickle cell disease (SCD) is associated with arthropathy. Arthropathy may require periarticular corticosteroid injection therapy. This observational study examines efficacy, and safety of steroid injections in SCD patients. Data collection includes patient's gender, age, race, smoking history, alcohol intake, analgesic use, pain score, sleep quality, limb joint injections, post-injection analgesia, and post-injection complication. Pain is measured using numeric pain scale. Sleep quality is measured using Likert scale.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 50 participants
Study completion date: March 31, 2024
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
January 30, 2018
Actual (reported)
First Submitted
August 1, 2023
Actual (reported)
First Posted
August 9, 2023
Actual (reported)
Primary Completion
March 31, 2024
Actual (reported)
Study Completion
March 31, 2024
Actual (reported)

Last Updated: January 27, 2025
Status Verified: January 2025
Last Update Submitted: January 23, 2025

Conditions

Sickle Cell Disease Sickle Cell Abnormality

Keywords

Sickle cell

Outcome Measures

Primary Outcomes (1)

Numeric pain score, objective measurement using validated Numeric Pain Rating scale
Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain
12 weeks

Secondary Outcomes (1)

Sleep quality score, objective measurement using validated Likert sleep scale
12 weeks

Interventions

Dexamethasone 20mgDrug

Periarticular dexamethasone injection

Also known as: Dexamethasone injection

Eligibility Criteria

Age20 Years - 99 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

A cohort of consecutive adult patients who underwent pain management at a pain clinic

You may qualify if:

adult chronic pain patients

Sponsors & Collaborators

Salem Anaesthesia Pain Clinic
Otherlead

Study Sites (1)

Salem Anaesthesia Pain Clinic

Surrey, British Columbia, V3S 7J1, Canada

MeSH Terms

Conditions

Anemia, Sickle Cell

Interventions

DexamethasoneCalcium Dobesilate

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, CongenitalAnemia, HemolyticAnemiaHematologic DiseasesHemic and Lymphatic DiseasesHemoglobinopathiesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Pregnadienetriols

Study Officials

Olumuyiwa Bamgbade, MD,FRCPC
Salem Anaesthesia Pain Clinic
PRINCIPAL INVESTIGATOR

Enrollment

50 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 1, 2023

First Posted

August 9, 2023

Study Start

January 30, 2018

Actual (reported)

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Phase 4Completed

sickle cell disease arthropathy

periarticular steroid injection therapy

regular sleep diary

regular pain diary

informed consent for therapy and diary review

You may not qualify if:

pediatric patients
patient without sickle cell disease arthropathy
patient without periarticular steroid injection
irregular sleep diary
irregular pain diary

Contact the study team to confirm eligibility.

Pregnadienes

Pregnanes

Steroids

Fused-Ring Compounds

Polycyclic Compounds

Steroids, Fluorinated

Benzenesulfonates

Benzene Derivatives

Hydrocarbons, Aromatic

Hydrocarbons, Cyclic

Hydrocarbons

Organic Chemicals

Arylsulfonates

Arylsulfonic Acids

Sulfonic Acids

Sulfur Acids

Sulfur Compounds

Primary Completion

March 31, 2024

Actual (reported)

Study Completion

March 31, 2024

Actual (reported)

Last Updated

January 27, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT05983055
Data provider: ClinicalTrials.gov
Source updated: 2025-01-27
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:31:28 UTC

Locations

CA(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations