NCT05982899

Brief Summary

To explore the predictive factors of frailty trajectories and develop a web-based nomogram among gastric cancer survivors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
412

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2021

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2021

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2023

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 22, 2023

Completed
18 days until next milestone

First Posted

Study publicly available on registry

August 9, 2023

Completed
Last Updated

August 9, 2023

Status Verified

August 1, 2023

Enrollment Period

1.6 years

First QC Date

July 22, 2023

Last Update Submit

August 1, 2023

Conditions

Gastric Cancer

Keywords

gastric cancer

Outcome Measures

Primary Outcomes (1)

  • frailty trajectories

    Frailty was measured by Tilburg frailty indicator (TFI) scale at discharge, one month, three months, six months and twelve months after surgery.

    1 year

Eligibility Criteria

Age60 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

elderly gastric cancer survivors

You may qualify if:

  • diagnosed with gastric cancer by endoscopy or pathology;
  • age ≥60 years old;
  • radical gastrectomy was proposed;
  • be able to communicate simply in writing and verbally.

You may not qualify if:

  • combined with other sites of malignant tumors;
  • combined with severe heart, liver, lung, and renal insufficiency;
  • recent using hormones, immunosuppressants;
  • with physical disabilities.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Xueyi Miao

Nanjing, Jiangsu, 211166, China

Location

Nanjing medical university

Nanjing, China

Location

Related Publications (2)

  • Guo Y, Miao X, Chen Y, Ding L, Zhao K, Xu T, Chen L, Xu X, Xu Q. Hypothetical Interventions on Frailty Heterogeneous Trajectories of Older Patients with Gastric Cancer Using Parametric G-Formula. Ann Surg Oncol. 2025 Oct;32(10):7634-7643. doi: 10.1245/s10434-025-18026-w. Epub 2025 Aug 9.

    PMID: 40783664DERIVED

  • Miao X, Guo Y, Ding L, Xu X, Zhao K, Zhu H, Chen L, Chen Y, Zhu S, Xu Q. A dynamic online nomogram for predicting the heterogeneity trajectories of frailty among elderly gastric cancer survivors. Int J Nurs Stud. 2024 May;153:104716. doi: 10.1016/j.ijnurstu.2024.104716. Epub 2024 Feb 13.

    PMID: 38412776DERIVED

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 22, 2023

First Posted

August 9, 2023

Study Start

March 1, 2021

Primary Completion

October 1, 2022

Study Completion

April 1, 2023

Last Updated

August 9, 2023

Record last verified: 2023-08

Locations

CN(2)