The Number of Mesogastria Containing Metastatic Lymph Nodes Predicts Gastric Cancer Prognosis

NCT06697821 | Completed

• 1 other identifier: TJ-IRB202403050
• Study Type: observational
• Target: 480
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the impact of the number of mesogastria containing metastatic lymph nodes on the prognosis of gastric cancer.

Conditions

Gastric Cancer

Keywords

metastasis; Gastric Cancer; Lymph node; Mesogastrium

Outcome Measures

Primary Outcomes (1)

• Overall survival

  Postoperative 5-year survival

  Postoperative 5-year survival

Secondary Outcomes (1)

• The Number of Mesogastria Containing Metastatic Lymph Nodes

  Postoperative 5-year

Interventions

D2＋CME PROCEDURE

Whether to perform the whole mesogastric excision

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with gastric cancer who underwent total or proximal gastrectomy in Tongji Hospital were included in this study

You may qualify if:

• older than 18, younger than 85
• primary gastric adenocarcinoma confirmed by preoperative pathology
• routine blood tests, liver and kidney functions and who health status score are within the range of tolerable surgery
• it is expected to perform radical gastrectomy through d2+cme

You may not qualify if:

• pregnant or lactating women
• severe mental disorder or language communication disorder
• preoperative imaging examination or intraoperative exploration found that the patient had the following conditions: tumor involving surrounding organs requiring combined organ resection, distant organ metastasis or R0 resection could not be achieved
• those who are not suitable for laparoscopic surgery (such as extensive adhesion caused by anterior abdominal surgery and pneumoperitoneum for various reasons).
• concurrent malignancies at other sites
• emergency surgery patients

Sponsors & Collaborators

• Jichao Qin: lead

Study Sites (1)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, 430000, China

Location

MeSH Terms

Conditions

Stomach Neoplasms; Neoplasm Metastasis

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases; Neoplastic Processes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Jichao Qin, M.D./Ph.D

  Huazhong University of Science and Technology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 18, 2024
• First Posted: November 20, 2024
• Study Start: May 1, 2020
• Primary Completion: May 1, 2023
• Study Completion: May 1, 2024
• Last Updated: November 25, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)