Determining How Indoor Lighting Affects the Brain Health of Older Adults
1 other identifier
interventional
70
1 country
1
Brief Summary
The goal of this randomized, cross-over, single-site trial followed by an exploratory third intervention is to understand how indoor lighting affects different measures of brain health in older adults living in independent living residences. This is a community based study occurring in a local senior living facility. The main question this study aims to answer is: \- How does the quality of ambient indoor lighting an older adult is exposed to affect measures of brain health, such as sleep quality, physical activity, cognitive function, and social engagement? Participants will be exposed to three different indoor lighting conditions for 4 weeks each while performing the following tasks:
- Wear a smartwatch throughout the study to measure sleep quality and physical activity
- Wear a small, wearable light sensor to measure light exposure during waking hours
- Perform cognitive assessments throughout the study to detect any changes between each of the lighting conditions
- Complete self-report of surveys to assess independence, social engagement, sleep quality, and mood Results from these tasks will be compared within and between subjects to assess whether the different lighting conditions affect these different measures of brain health.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2023
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 27, 2023
CompletedStudy Start
First participant enrolled
May 15, 2023
CompletedFirst Posted
Study publicly available on registry
August 7, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2023
CompletedAugust 7, 2023
July 1, 2023
7 months
April 27, 2023
July 28, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
Total Sleep Time
Total sleep time per night in minutes as measured daily by a wearable device.
Change in total sleep time per night over the course of each condition of the 16-week study.
Wake After Sleep Onset
Wake after sleep onset per night in minutes as measured daily by a wearable device.
Change in wake after sleep onset per night over the course of each condition of the 16-week study.
Sleep State Duration
Sleep state duration per night in minutes as measured daily by a wearable device.
Change in sleep state duration per night over the course of each condition of the 16-week study.
Secondary Outcomes (10)
Sleep Quality
Change in self-reported sleep quality over the course of each condition of the 16-week study.
Steps Taken
Change in physical activity in steps per day over the course of each condition of the 16-week study.
Physical Activity
Change in physical activity in minutes per day over the course of each condition of the 16-week study.
Working Memory
Change in working memory performance over the course of each condition of the 16-week study.
Task Switching
Change in task switching performance over the course of each condition of the 16-week study.
- +5 more secondary outcomes
Study Arms (2)
L1 then L2 followed by L3 lighting condition
ACTIVE COMPARATORParticipants will first experience a static lighting condition (L1) then a dynamic lighting condition (L2). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L2 then L1 followed by L3 lighting condition
ACTIVE COMPARATORParticipants will first experience a dynamic lighting condition (L2) then a static lighting condition (L1). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
Interventions
This indoor lighting condition keeps a constant brightness and correlated color temperature.
This indoor lighting condition has increased brightness and more blue correlated color temperature in the morning hours followed by decreased brightness and less blue correlated color temperature in the afternoon and evening hours.
This exploratory indoor lighting condition matches the same pattern as L2 except the brightness in the morning hours is increased.
Eligibility Criteria
You may qualify if:
- At least age 60;
- Able to wear wearable devices throughout the study;
- Willing to have their lighting in their kitchen and dining areas changed and controlled for the study;
- Willing to have environmental sensors placed in their residence;
- Willing to provide contact information about their primary care provider (PCP); and
- Able and has capacity to provide informed consent (score \> 14.5 based on UBACC consent capacity form).
You may not qualify if:
- Is legally blind
- Previously renovated their living units and no longer have the standard lighting installation offered by the Senior Living Facility;
- Currently spend or plan to spend most of their day outside of their residence during the study (i.e., would not experience the indoor lighting intervention for the majority of the study);
- Plan to travel to a different time zone during the study; or
- Plan to be away from their residence for more than a week during the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Well Living Lab, Inc.lead
- Mayo Cliniccollaborator
Study Sites (1)
The Waters on Mayowood
Rochester, Minnesota, 55901, United States
Related Publications (1)
Mazurek KA, Li L, Klein RJ, Rong S, Mullan AF, Jones DT, St Louis EK, Worrell GA, Chen CY. Investigating the effects of indoor lighting on measures of brain health in older adults: protocol for a cross-over randomized controlled trial. BMC Geriatr. 2024 Oct 11;24(1):816. doi: 10.1186/s12877-023-04594-7.
PMID: 39394603DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 27, 2023
First Posted
August 7, 2023
Study Start
May 15, 2023
Primary Completion
December 1, 2023
Study Completion
December 1, 2023
Last Updated
August 7, 2023
Record last verified: 2023-07
Data Sharing
- IPD Sharing
- Will not share