Improving Sleep in the Neurology In-Patient Population

NCT06094699 | Completed

• 1 other identifier: 850574
• Study Type: interventional
• Target: 145
• Locations: 1 country
• Sites: 1

Brief Summary

We aim to test multiple interventions to improve sleep for Neurology inpatients, including 1) a sleep-friendly order set, and 2) a sleep menu. We will collect patient sleep data, including duration and quality, via actigraphy devices (FitBits). We will also conduct qualitative patient surveys to understand the impact of these interventions.

Conditions

Sleep

Outcome Measures

Primary Outcomes (1)

• Fitbit Sleep Duration

  Total hours of sleep

  Duration of hospitalization from consent to discharge or day 10, whichever comes first

Secondary Outcomes (3)

• FitBit sleep score

  Duration of hospitalization from consent to discharge or day 10, whichever comes first

• Richard Campbell Sleep Questionnaire (RCSQ)

  Duration of hospitalization from consent to discharge or day 10, whichever comes first

• Patient reported Sleep Duration and Quality

  Duration of hospitalization from consent to discharge or day 10, whichever comes first

Study Arms (2)

Standard of care

NO INTERVENTION

Sleep intervention

EXPERIMENTAL

Other: Sleep friendly order set; Other: Patient sleep menu

Interventions

Sleep friendly order set OTHER

Every evening, the following orders (which comprise the sleep-friendly order set) will be input into the EMR: Hold vital signs and neurological checks overnight Retime applicable medications outside of the nighttime window of 10pm-6am Retime daily lab draws outside of the nighttime window of 10pm-6am Order melatonin if no clinical contraindications Discontinue finger stick glucose measurements for patients with a stable blood glucose values Change DVT prophylaxis to enoxaparin for all clinically eligible patients

Sleep intervention

Patient sleep menu OTHER

Patients will be given a menu of non-pharmacological options that support sleep by improving comfort and reducing anxiety.

Sleep intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18
• hours after admission to the general neurology (ward) service at the Hospital of the University of Pennsylvania
• Patients who are determined by the primary team to be clinically stable enough to forego serial overnight vital signs monitoring and neuro checks.
• Clinical stability criteria:
• Symptomatic stability \>24h after admission (no new or progressive neurologic symptoms for \>24 hours)
• Vital signs stability on admission for \> 24h while admitted
• Ability to verbally consent to study participation

You may not qualify if:

• Any medical or psychological conditions that, in the opinion of the investigator, would compromise the subject's safety or successful participation in the study.
• Any additional clinical factors felt by the team to be incompatible with specific orders including requiring serial vital signs monitoring and neuro checks overnight

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (1)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Study Officials

• Laura Stein

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investgiator

Study Record Dates

• First Submitted: October 16, 2023
• First Posted: October 23, 2023
• Study Start: April 30, 2023
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: August 8, 2025

Record last verified: 2025-08

Locations

US (1)