Impact of Physical and Occupational Therapy in New BMT Patients

NCT05978583 | Completed DMC

• 1 other identifier: LCCC2252
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

This is a single-site, non-randomized, observational study designed to evaluate the impact of adding physical and occupational therapy consultation upon inpatient admission for a bone marrow transplantation (BMT). The purpose of this study is to investigate whether consultation with physical and occupational therapists as part of the general admission order set for patients scheduled for bone marrow transplant will result in reduced complications, morbidity, length of inpatient stay, 30-day readmission, and 90-day mortality. Baseline data collection will be used to determine eligibility. This study will be partially retrospective (pre-implementation of physical and occupational therapy consultation order) and partially prospective.

Conditions

Bone Marrow Transplantation; Bone Marrow Disease

Keywords

exercise; physical therapy

Outcome Measures

Primary Outcomes (1)

• 30-day readmission

  30-day readmission rates will be calculated using historical data (pre-intervention) and compared to rates once physical and occupational therapy consultation has been included in the inpatient admission order set for bone marrow transplantation (BMT).

  Up to 30 days after bone marrow transplantation

Secondary Outcomes (4)

• The feasibility

  1 day (the date of bone marrow transplantation)

• Acute care length of stay

  Up to 90 days after bone marrow transplantation

• Mortality rates

  Up to 90 days after bone marrow transplantation

• Complication types and rates

  Up to 90 days after bone marrow transplantation

Study Arms (1)

physical and occupational therapy

Physical and occupational therapy consultation might be used to provide targeted prehabilitation interventions.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects who are admitted for bone marrow transplantation (BMT) at the study site.

You may qualify if:

• Age ≥ 18 years at the time of admission for bone marrow transplantation (BMT)
• Received BMT

You may not qualify if:

• \. No history of inpatient admission for BMT

Sponsors & Collaborators

• UNC Lineberger Comprehensive Cancer Center: lead

Study Sites (1)

Lineberger Comphrehensive Cancer Center at University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

Location

Related Links

• University of North Carolina Lineberger Comprehensive Cancer Center Clinical Trials

MeSH Terms

Conditions

Bone Marrow Diseases; Motor Activity

Condition Hierarchy (Ancestors)

Hematologic Diseases; Hemic and Lymphatic Diseases; Behavior

Study Officials

• Sasha Stephen, MD

  UNC Lineberger Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2023
• First Posted: August 7, 2023
• Study Start: January 1, 2023
• Primary Completion: December 4, 2024
• Study Completion: December 4, 2024
• Last Updated: December 15, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)