NCT00004994

Brief Summary

This study will examine the quality of life of patients undergoing bone marrow transplantation to treat a blood disease. It will look at how this therapy affects many areas of life, including for example, personal relationships, work, and general emotional state. The information gained may lead to improved ways of dealing with problems that may arise before or during treatment. Patients receiving bone marrow stem cells donated by a family member may participate in this study. They will be interviewed before treatment begins and will complete questionnaires at the following intervals:

  1. 1.day of admission to the hospital
  2. 2.day of the transplant
  3. 3.30 days after the transplant
  4. 4.100 days after the transplant
  5. 5.1 year after therapy
  6. 6.2 years after therapy

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
106

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 1999

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 1999

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

March 22, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 23, 2000

Completed
4.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2004

Completed
Last Updated

March 4, 2008

Status Verified

October 1, 2004

First QC Date

March 22, 2000

Last Update Submit

March 3, 2008

Conditions

Bone Marrow Transplantation

Keywords

Allogeneic TransplantFunctionMini-TransplantPhysical SymptomsSymptom Distress

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female subjects 18 years of age or older.
  • Able to read English or Spanish.
  • Hematological disease requiring A-PBSCT.
  • Signed informed consent for QOL study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Warren G. Magnuson Clinical Center (CC)

Bethesda, Maryland, 20892, United States

Location

Related Publications (3)

  • Andrykowski MA, Henslee PJ, Farrall MG. Physical and psychosocial functioning of adult survivors of allogeneic bone marrow transplantation. Bone Marrow Transplant. 1989 Jan;4(1):75-81.

    PMID: 2647190BACKGROUND

  • Andrykowski MA, Altmaier EM, Barnett RL, Otis ML, Gingrich R, Henslee-Downey PJ. The quality of life in adult survivors of allogeneic bone marrow transplantation. Correlates and comparison with matched renal transplant recipients. Transplantation. 1990 Sep;50(3):399-406. doi: 10.1097/00007890-199009000-00009.

    PMID: 2402788BACKGROUND

  • Baker F, Wingard JR, Curbow B, Zabora J, Jodrey D, Fogarty L, Legro M. Quality of life of bone marrow transplant long-term survivors. Bone Marrow Transplant. 1994 May;13(5):589-96.

    PMID: 8054912BACKGROUND

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

March 22, 2000

First Posted

March 23, 2000

Study Start

October 1, 1999

Study Completion

October 1, 2004

Last Updated

March 4, 2008

Record last verified: 2004-10

Locations

US(1)